Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268158 | 1.00 | HTR2B (0.47) | HTR2BGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL15047709 | 0.89 | HTR2B (0.46) | HTR2BALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL15602761 | 0.87 | ALDH1A1 (0.47) | HTR2BGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL15602762 | 0.87 | ALDH1A1 (0.47) | HTR2BGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL15047712 | 0.84 | HTR2B (0.43) | HTR2BALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3328808 | 0.84 | MAPT (0.43) | HTR2BGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL26119968 | 0.83 | HTR2B (0.50) | HTR2BGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL26119975 | 0.83 | HTR2B (0.50) | HTR2BGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL15602812 | 0.82 | HTR2B (0.59) | HTR2BGPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL15602915 | 0.82 | HTR2B (0.59) | HTR2BGPR35ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879886-B2 | such as N-benzyl-N-hydroxy-2-(3-hydoxypyridin-2-ene)-1,3-thiazolidine-4-carboxamide, used for reducing the population of Plasmodium in a human infested with Plasmodium protozoans and suffering from malaria | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20070232664-A1 | Iron binding agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-10-04 | — | — | US | disclosed |
| US-7144904-B2 | desferrithiocin analogs used as siderophores, for treatment of malaria in humans | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2006-12-05 | — | — | US | disclosed |
| US-20050245579-A1 | Iron binding agents | BERGERON RAYMOND J JR | 2005-11-03 | — | — | US | disclosed |
| US-6864270-B2 | Iron binding agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| EP-1488791-A2 | Antimalarial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2004-12-22 | — | — | EP | disclosed |
| US-20030083349-A1 | Iron binding agents | UNIVERSITY OF FLORIDA (US) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232664-A1 | Iron binding agents | TFRC, SLC40A1, FECH | HTR2B 3804/4885GPR35 2133/4885ALDH1A1 2200/4885 |
| US-20050245579-A1 | Iron binding agents | TFRC, SLC40A1, FECH | HTR2B 3804/4885GPR35 2133/4885ALDH1A1 2200/4885 |
| US-20030083349-A1 | Iron binding agents | TFRC, SLC40A1, FECH | HTR2B 3804/4885GPR35 2133/4885ALDH1A1 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.