Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15047709 | 0.88 | HTR2B (0.46) | HTR2BMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1268161 | 0.84 | HTR2B (0.47) | HTR2BMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL1268158 | 0.84 | HTR2B (0.47) | HTR2BMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL5623050 | 0.80 | ALDH1A1 (0.45) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3954380 | 0.80 | ALDH1A1 (0.45) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13549371 | 0.79 | HTR2B (0.41) | HTR2BTDP1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL15047161 | 0.78 | HTR2B (0.43) | HTR2BTDP1MAPTALDH1A1KDM4E | |
| SCHEMBL16203066 | 0.76 | MEN1 (0.43) | HTR2BMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL27950276 | 0.76 | KDM4E (0.44) | HTR2BTDP1MAPTALDH1A1KDM4E | |
| SCHEMBL5914830 | 0.75 | TSHR (0.46) | HTR2BMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323534-A1 | USES OF 3'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-10-30 | — | — | US | disclosed |
| WO-2013090766-A1 | USES OF 3'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323534-A1 | USES OF 3'-DESFERRITHIOCIN ANALOGS | TFRC, AIFM2, FTH1 | HTR2B 914/4885TDP1 3819/4885CTDSP1 4675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.