SCHEMBL1438720

SCHEMBL1438720

COc1c(C(=O)O)ccc(O)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
MAPT P10636 2/20 0.59
SELL P14151 1/20 0.57
SELP P16109 1/20 0.57
HTT P42858 2/20 0.43
CSNK2A1 P68400 1/20 0.42
TPMT P51580 4/20 0.42
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
POLB P06746 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PDE4A P27815 1/20 0.41
BLVRB P30043 1/20 0.41
KDR P35968 1/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419245 0.86 TDP1 (0.56) TDP1MAPTSELLSELPHTT
SCHEMBL12683255 0.84 TDP1 (0.70) TDP1MAPTSELLSELPHTT
SCHEMBL13827071 0.84 ALDH1A1 (0.52) TDP1MAPTSELLSELPHTT
SCHEMBL1505827 0.83 TDP1 (0.61) TDP1MAPTHTTALDH1A1HSD17B10
SCHEMBL16173476 0.82 CA12 (0.52) TDP1MAPTALDH1A1POLBMEN1
SCHEMBL11026756 0.82 MAPT (0.73) TDP1MAPTHTTTPMTALDH1A1
SCHEMBL28841565 0.82 TDP1 (0.58) TDP1MAPTSELLSELPALDH1A1
SCHEMBL6474772 0.82 TDP1 (0.58) TDP1MAPTSELLSELPHTT
SCHEMBL22245019 0.81 TDP1 (0.56) TDP1MAPTSELLSELPTPMT
SCHEMBL27544371 0.81 TDP1 (0.51) TDP1MAPTSELLSELPHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2470632-A1 IMPROVED WASHING PERFORMANCE USING RADICAL TRAPS Henkel AG & Co. KGaA (DE) 2012-07-04 EP claimed
US-20120157370-A1 WASHING PERFORMANCE USING RADICAL TRAPS HENKEL AG & CO. KGAA (DE) 2012-06-21 US claimed
WO-2011023716-A1 IMPROVED WASHING PERFORMANCE USING RADICAL TRAPS HENKEL AG & CO. KGAA (DE) 2011-03-03 WO claimed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20210397090-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION AND METHOD FOR FORMING RESIST PATTERN USING THE SAME NISSAN CHEMICAL CORPORATION (JP) 2021-12-23 US disclosed
US-20140309220-A1 BENZOXAZINES AS MODULATORS OF ION CHANNELS VERTEX PHARMACEUTICALS INCORPORATED 2014-10-16 US disclosed
US-20140309220-A1 BENZOXAZINES AS MODULATORS OF ION CHANNELS VERTEX PHARMACEUTICALS INCORPORATED 2014-10-16 US disclosed
CN-102998924-A Toner CANON KK 2013-03-27 CN disclosed
CN-102789146-A Toner CANON KK 2012-11-21 CN disclosed
CN-102789147-A Toner CANON KK 2012-11-21 CN disclosed
US-20120157370-A1 WASHING PERFORMANCE USING RADICAL TRAPS HENKEL AG & CO. KGAA (DE) 2012-06-21 US disclosed
US-4191841-A DEMETHYLATION USING AN ALKALI HYDROXIDE AND ETHYLENE GLYCOL SOCIETE FRANCAISE HOECHST (FR) 1980-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140309220-A1 BENZOXAZINES AS MODULATORS OF ION CHANNELS KCNJ1, KCNJ2, KCNJ11 TDP1 2594/4885MAPT 1992/4885SELL 4204/4885
US-20120157370-A1 WASHING PERFORMANCE USING RADICAL TRAPS MPO, DNASE1, PLD4 TDP1 201/4885MAPT 2017/4885SELL 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.