Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899168 | 0.82 | CA1 (0.38) | CA12CA1CA2CA4CA7 | |
| SCHEMBL7186706 | 0.73 | CA4 (0.33) | CA12CA1CA2CA4CA7 | |
| SCHEMBL1688313 | 0.73 | TSHR (0.43) | CA12CA1CA2CA4CA7 | |
| SCHEMBL767433 | 0.72 | — | — | |
| SCHEMBL1713269 | 0.71 | CA1 (0.55) | IDO1CA12CA1CA2CA4 | |
| SCHEMBL1983082 | 0.71 | MAPT (0.54) | — | |
| SCHEMBL7186712 | 0.71 | TSHR (0.44) | CA12CA1CA2CA4CA7 | |
| SCHEMBL15097501 | 0.71 | ACHE (0.39) | IDO1 | |
| SCHEMBL943060 | 0.71 | APOBEC3G (0.46) | IDO1 | |
| SCHEMBL8006473 | 0.71 | MEN1 (0.33) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012110860-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2012-08-23 | — | — | WO | disclosed |