Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21148523 | 0.85 | HAO1 (0.43) | APOBEC3GTAAR1 | |
| SCHEMBL22145829 | 0.85 | MEN1 (0.36) | MEN1MAPTKMT2ANPSR1APOBEC3G | |
| SCHEMBL20222308 | 0.85 | LMNA (0.47) | PDE7A | |
| SCHEMBL3609852 | 0.84 | TUBB4A (0.45) | MEN1MAPTKMT2AMGLLSMN1; SMN2 | |
| SCHEMBL22155791 | 0.82 | DHFR (0.36) | CYP1A2CYP3A4 | |
| SCHEMBL943060 | 0.81 | APOBEC3G (0.46) | MEN1MAPTKMT2ANPSR1APOBEC3G | |
| SCHEMBL18508311 | 0.79 | — | — | |
| SCHEMBL17156541 | 0.77 | HTR1A (0.51) | MEN1MAPTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL23986125 | 0.77 | — | — | |
| SCHEMBL29123914 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620848-A | Reaction method of thiophenol and o-diiodobenzene | 苏州大学 | 2021-11-09 | — | — | CN | claimed |
| CN-113735751-B | Method for preparing aryl isothiourea | 上海药坦药物研究开发有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-113735751-A | Method for preparing aryl isothiourea | 上海药坦药物研究开发有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113620848-A | Reaction method of thiophenol and o-diiodobenzene | 苏州大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-113620848-A | Reaction method of thiophenol and o-diiodobenzene | 苏州大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-103787802-B | One class arylalkyl thioethers compound and synthetic method thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2015-08-19 | — | — | CN | disclosed |
| EP-2460802-B1 | TRIFLUOROMETHYLTHIOPHENIUM DERIVATIVE SALTS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF TRIFLUOROMETHYL-CONTAINING COMPOUNDS USING SAME | NAGOYA INST TECHNOLOGY (JP) | 2014-09-03 | — | — | EP | disclosed |
| CN-103787802-A | Aryl alkyl thioether compounds and synthesis method thereof | UNIV EAST CHINA NORMAL | 2014-05-14 | — | — | CN | disclosed |
| EP-2460802-A1 | TRIFLUOROMETHYLTHIOPHENIUM DERIVATIVE SALTS, PROCESS FOR PRODUCITON THEREOF, AND PROCESS FOR PRODUCTION OF TRIFLUOROMETHYL-CONTAINING COMPOUNDS USING SAME | Nagoya Institute of Technology (JP) | 2012-06-06 | — | — | EP | disclosed |
| WO-2000024694-A1 | PHOTOCHEMICAL PROCESS FOR MAKING 1-DEOXY-2-KETO DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-05-04 | — | — | WO | disclosed |
| US-5268449-A | Containing arylene sulfide and arylene sulfonate segments | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |