Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899168 | 0.84 | CA1 (0.38) | CA4CA12CA1CA2CA7 | |
| SCHEMBL1688313 | 0.75 | TSHR (0.43) | CA4CA12CA1CA2CA7 | |
| SCHEMBL20665030 | 0.75 | ACHE (0.41) | POLBHSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL13784392 | 0.75 | GABRA1 (0.41) | CA1CA2LMNACYP1A2CYP3A4 | |
| SCHEMBL7186712 | 0.73 | TSHR (0.44) | CA4CA12CA1CA2CA7 | |
| SCHEMBL15097501 | 0.73 | ACHE (0.39) | POLBALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL12686351 | 0.73 | IDO1 (0.32) | CA4CA12CA1CA2CA7 | |
| SCHEMBL1713269 | 0.73 | CA1 (0.55) | CA4CA12CA1CA2CA7 | |
| SCHEMBL1983082 | 0.73 | MAPT (0.54) | POLBHSD17B10KDM4EGMNNALDH1A1 | |
| SCHEMBL7526557 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192178-A2 | RUFOMYCINS AND DERIVATIVES THEREOF USEFUL AS INHIBITORS OF MULTI-DRUG RESISTANCE ASSOCIATED PROTEIN-1 (MRP-1) | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | claimed |
| WO-2000078795-A2 | RUFOMYCINS AND DERIVATIVES THEREOF USEFUL AS INHIBITORS OF MULTI-DRUG RESISTANCE ASSOCIATED PROTEIN-1 (MRP-1) | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | claimed |
| US-11739171-B2 | Method for producing α-olefin/(meth)acrylic acid ester copolymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2023-08-29 | — | — | US | disclosed |
| CN-111971310-B | Process for producing alpha-olefin/(meth) acrylate copolymer | 日本聚乙烯株式会社 | 2023-07-18 | — | — | CN | disclosed |
| US-20210122853-A1 | METHOD FOR PRODUCING alpha-OLEFIN/(METH)ACRYLIC ACID ESTER COPOLYMER | JAPAN POLYETHYLENE CORPORATION (JP) | 2021-04-29 | — | — | US | disclosed |
| EP-3800207-A1 | METHOD FOR PRODUCING & ALPHA-OLEFIN/(METH)ACRYLIC ACID ESTER COPOLYMER | Japan Polyethylene Corporation (JP) | 2021-04-07 | — | — | EP | disclosed |
| CN-111971310-A | Process for producing alpha-olefin/(meth) acrylate copolymer | 日本聚乙烯株式会社 | 2020-11-20 | — | — | CN | disclosed |
| WO-2019188499-A1 | METHOD FOR PRODUCING α-OLEFIN/(METH)ACRYLIC ACID ESTER COPOLYMER | 日本ポリエチレン株式会社 | 2019-10-03 | — | — | WO | disclosed |
| US-6627714-B2 | Copolymerizing ethylene and dicyclopentadiene or tricyclopentadiene, and cyclic olefin in presence of metallocene catalyst to produce copolymer | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| US-20020058767-A1 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-16 | — | — | US | disclosed |
| EP-1205497-A2 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |