Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899168 | 0.82 | CA1 (0.38) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL3686152 | 0.80 | CA2 (0.45) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL10978453 | 0.79 | TSHR (0.45) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL10305662 | 0.78 | ALDH1A1 (0.43) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL20150459 | 0.76 | ALDH1A1 (0.40) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL6655975 | 0.74 | THRB (0.39) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL7186706 | 0.73 | CA4 (0.33) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL1688313 | 0.73 | TSHR (0.43) | TSHRCA2CA1LMNAALDH1A1 | |
| SCHEMBL22168530 | 0.73 | CA2 (0.46) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL337809 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666854-B | Preparation method of symmetrical disulfide bond-containing compound | 南京工业大学 | 2022-04-12 | — | — | CN | claimed |
| CN-113666854-A | Preparation method of symmetrical disulfide bond-containing compound | 南京工业大学 | 2021-11-19 | — | — | CN | claimed |
| CN-1696121-A | 4-[2-(artyl sulfo) benzyl]-1-derivative of aryl-piperazine, preparation method and application | UNIV TIANJIN (CN) | 2005-11-16 | — | — | CN | claimed |
| EP-1192178-A2 | RUFOMYCINS AND DERIVATIVES THEREOF USEFUL AS INHIBITORS OF MULTI-DRUG RESISTANCE ASSOCIATED PROTEIN-1 (MRP-1) | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | claimed |
| WO-2000078795-A2 | RUFOMYCINS AND DERIVATIVES THEREOF USEFUL AS INHIBITORS OF MULTI-DRUG RESISTANCE ASSOCIATED PROTEIN-1 (MRP-1) | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | claimed |
| US-11739171-B2 | Method for producing α-olefin/(meth)acrylic acid ester copolymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2023-08-29 | — | — | US | disclosed |
| CN-111971310-B | Process for producing alpha-olefin/(meth) acrylate copolymer | 日本聚乙烯株式会社 | 2023-07-18 | — | — | CN | disclosed |
| CN-113666854-B | Preparation method of symmetrical disulfide bond-containing compound | 南京工业大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-113666854-A | Preparation method of symmetrical disulfide bond-containing compound | 南京工业大学 | 2021-11-19 | — | — | CN | disclosed |
| EP-3594202-B1 | SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-08-11 | — | — | EP | disclosed |
| US-20210122853-A1 | METHOD FOR PRODUCING alpha-OLEFIN/(METH)ACRYLIC ACID ESTER COPOLYMER | JAPAN POLYETHYLENE CORPORATION (JP) | 2021-04-29 | — | — | US | disclosed |
| EP-3800207-A1 | METHOD FOR PRODUCING & ALPHA-OLEFIN/(METH)ACRYLIC ACID ESTER COPOLYMER | Japan Polyethylene Corporation (JP) | 2021-04-07 | — | — | EP | disclosed |
| EP-0062615-B1 | DERIVATIVES OF TETRASUBSTITUTED PHTHALIC ACID , PROCESS FOR THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |
| US-4472586-A | 6H-Dibenz[b,e][1,4]oxathiepin derivatives | MERCK FROSST CANADA, INC. (CA) | 1984-09-18 | — | — | US | disclosed |
| US-4459414-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1984-07-10 | — | — | US | disclosed |
| EP-0105692-A1 | 6-H-dibenz(b,e)(1,4)oxathiepin derivatives and their preparation | MERCK FROSST CANADA INC. (CA) | 1984-04-18 | — | — | EP | disclosed |
| EP-0062615-A1 | Derivatives of tetrasubstituted phthalic acid , process for their preparation and use | CIBA-GEIGY AG (CH) | 1982-10-13 | — | — | EP | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |