SCHEMBL1268684

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7829368	0.93	TLR8 (0.40)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL7829823	0.89	NOS2 (0.36)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL1268563	0.81	TDP1 (0.39)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL5567705	0.76	TDP1 (0.38)	GABRA2GABRB2TLR8CTRCTYR
	SCHEMBL7832727	0.74	ALOX5 (0.40)	GABRA2GABRB2TLR8TYRTDP1
	SCHEMBL7831257	0.72	NOS2 (0.38)	GABRA1GABRB2NOS2TDP1NOS3
	SCHEMBL7832945	0.68	TDP1 (0.41)	ALDH1A1TDP1
	SCHEMBL27371741	0.67	CTRC (0.39)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL13040091	0.67	TYR (0.38)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL833088	0.66	SKP2 (0.47)	GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.