Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28304525 | 0.77 | CCR1 (0.55) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL8193 | 0.77 | CCR1 (0.55) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL29354893 | 0.77 | CCR1 (0.55) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL1089189 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL16502269 | 0.76 | CCR1 (0.70) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Water SCHEMBL8327751 | 0.75 | CCR1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL2732606 | 0.75 | CCR1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL16337846 | 0.75 | CCR1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2284189 | 0.75 | CCR1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3704753 | 0.75 | CCR1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230097866-A1 | BACTERIAL TOPOISOMERASE INHIBITORS DERIVED FROM ISOMANNIDE | OHIO STATE INNOVATION FOUNDATION | 2023-03-30 | — | — | US | disclosed |
| EP-4093216-A1 | BACTERIAL TOPOISOMERASE INHIBITORS DERIVED FROM ISOMANNIDE | Ohio State Innovation Foundation (US) | 2022-11-30 | — | — | EP | disclosed |
| WO-2021150954-A1 | BACTERIAL TOPOISOMERASE INHIBITORS DERIVED FROM ISOMANNIDE | OHIO STATE INNOVATION FOUNDATION (US) | 2021-07-29 | — | — | WO | disclosed |
| CN-106046043-B | A kind of synthetic method of trialkyl (alpha-alkoxy base ethylene) tin | 无锡贝塔医药科技有限公司 | 2018-07-17 | — | — | CN | disclosed |
| EP-2740479-B1 | COMPOSITION CONTAINING ANTIBIOTICS AND LYSOPHOSPHATIDYLCHOLINE FOR BOOSTING IMMUNITY OR TREATMENT OF BACTERIAL INFECTIONS | ARIBIO INC (KR) | 2017-10-25 | — | — | EP | disclosed |
| CN-103781483-B | Composition containing antibiotics and lysophosphatidylcholine for boosting immunity or treatment of bacterial infections | 株式会社阿丽派欧 | 2017-04-26 | — | — | CN | disclosed |
| CN-104781251-B | Can as kinase modulator through the substituted pyridinyl compounds of bicyclic heterocycle | 百时美施贵宝公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-106046043-A | Trialkyl(alpha-alkoxy ethylene)tin synthesis method | 无锡贝塔医药科技有限公司 | 2016-10-26 | — | — | CN | disclosed |
| US-9446061-B2 | Composition containing antibiotics and lysophosphatidylcholine for boosting immunity or treatment of bacterial infections | ARIMED INC. (KR) | 2016-09-20 | — | — | US | disclosed |
| CN-103755710-B | One class 2,5-diazabicyclo iieptanes compound and application thereof | KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-08-12 | — | — | CN | disclosed |
| EP-2265120-B1 | HERBICIDAL COUMPOUNDS | SYNGENTA LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2265120-A1 | HERBICIDAL COUMPOUNDS | Syngenta Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009115788-A1 | HERBICIDAL COUMPOUNDS | SYNGENTA LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |
| US-7432279-B2 | 4,6-diamino-[1,7]naphthyridine-3-carbonitrile inhibitors of Tpl2 kinase and methods of making and using the same | WYETH (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1881981-A1 | 4, 6-DIAMINO-[1,7] NAPHTHYRIDINE-3-CARBONITRILE INHIBITORS OF TPL2 KINASE AND METHODS OF MAKING AND USING THE SAME | Wyeth (US) | 2008-01-30 | — | — | EP | disclosed |
| US-20060276498-A1 | 4,6-diamino-[1,7]naphthyridine-3-carbonitrile inhibitors of Tpl2 kinase and methods of making and using the same | WYETH (US) | 2006-12-07 | — | — | US | disclosed |
| WO-2006124944-A1 | 4, 6-DIAMINO-[1,7] NAPHTHYRIDINE-3-CARBONITRILE INHIBITORS OF TPL2 KINASE AND METHODS OF MAKING AND USING THE SAME | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |
| CN-1158120-A | Process for the preparation of antimicrobial compounds | PROCTER & GAMBLE (US) | 1997-08-27 | — | — | CN | disclosed |
| CN-86102683-A | The preparation method of antimicrobial drug | — | 1986-12-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230097866-A1 | BACTERIAL TOPOISOMERASE INHIBITORS DERIVED FROM ISOMANNIDE | TOP2A, TOP1, TOP2B | ALDH1A1 3472/4885LMNA 1880/4885KDM4E 2887/4885 |
| US-20060276498-A1 | 4,6-diamino-[1,7]naphthyridine-3-carbonitrile inhibitors of Tpl2 kinase and methods of making and using the same | TNNI3K, CNKSR1, DTYMK | ALDH1A1 1514/4885LMNA 2470/4885KDM4E 1953/4885 |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | RDX, NQO2, DDT | ALDH1A1 677/4885LMNA 2087/4885KDM4E 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.