SCHEMBL12690296

SCHEMBL12690296

CCCC1C(C)=C([SiH](C)C)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.36
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
HTR5A P47898 1/20 0.33
PBRM1 Q86U86 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
CYP1A2 P05177 2/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28290982 0.76 HTR2A (0.38) HTR2ABCHEACHEHTR5APBRM1
SCHEMBL1996543 0.76 HTR2A (0.54) HTR2ABCHEACHECYP1A2CYP2C19
SCHEMBL7779528 0.72 GPR3 (0.32)
SCHEMBL28292393 0.69 HTR2A (0.38) HTR2ABCHEACHEHTR5APBRM1
SCHEMBL2231675 0.69 HRH1 (0.35) HTR2ABCHEACHECYP1A2CYP2C19
SCHEMBL9075350 0.69 HTR2A (0.45) HTR2AACHEPBRM1TNKS2
SCHEMBL313685 0.66 ACHE (0.55) HTR2ABCHEACHE
SCHEMBL31619967 0.66 BCHE (0.39) HTR2ABCHEACHE
SCHEMBL877438 0.65 HTR2A (0.56) HTR2ABCHEACHE
SCHEMBL6061696 0.63 HTR2A (0.54) HTR2ABCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841397-B2 Vinyl terminated higher olefin polymers and methods to produce thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-09-23 US disclosed
US-8816027-B2 Catalysts and methods of use thereof to produce vinyl terminated polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-08-26 US disclosed
US-20130310528-A1 Novel Catalysts and Methods of Use Thereof to Produce Vinyl Terminated Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2013-11-21 US disclosed
US-8455597-B2 Catalysts and methods of use thereof to produce vinyl terminated polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-06-04 US disclosed
US-8426659-B2 Vinyl terminated higher olefin polymers and methods to produce thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-23 US disclosed
US-20130023633-A1 Vinyl Terminated Higher Olefin Polymers and Methods to Produce Thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-01-24 US disclosed
US-20120245311-A1 Novel Catalysts And Methods Of Use Thereof To Produce Vinyl Terminated Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2012-09-27 US disclosed
US-20120245312-A1 Vinyl Terminated Higher Olefin Polymers and Methods to Produce Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-09-27 US disclosed