Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.48 |
| ▸ | AOC2 | O75106 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602194 | 0.81 | ALOX15 (0.60) | ALOX15MAOBAOC3AOC2MAOA | |
| SCHEMBL7261032 | 0.81 | ALOX15 (0.60) | ALOX15MAOBAOC3AOC2MAOA | |
| SCHEMBL5707676 | 0.81 | ALOX15 (0.60) | ALOX15MAOBAOC3AOC2MAOA | |
| SCHEMBL27107740 | 0.81 | ALOX15 (0.61) | ALOX15ALDH1A1KMT2AMEN1 | |
| SCHEMBL11114121 | 0.79 | ALOX15 (0.59) | ALOX15MAOBAOC2MAOAALDH1A1 | |
| SCHEMBL2031455 | 0.79 | ALOX15 (0.58) | ALOX15MAOBAOC3AOC2MAOA | |
| SCHEMBL13780482 | 0.78 | PTPN7 (0.61) | ALDH1A1RECQLKMT2AMEN1HPGD | |
| SCHEMBL1221676 | 0.77 | WDR5 (0.64) | ALOX15MAOBAOC3AOC2MAOA | |
| SCHEMBL159433 | 0.77 | ALOX15 (0.56) | ALOX15MAOBAOC3AOC2MAOA | |
| SCHEMBL138162 | 0.77 | ALOX15 (0.68) | ALOX15ALDH1A1KMT2AMEN1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012129564-A2 | PROTEASOME CHYMOTRYPSIN-LIKE INHIBITION USING PI-1833 ANALOGS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2012-09-27 | — | — | WO | disclosed |