Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | AGXT | P21549 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478177 | 0.81 | PTPN7 (0.71) | PTPN7AGXTMEN1KMT2AHTT | |
| SCHEMBL8430491 | 0.81 | PTPN7 (0.61) | PTPN7AGXTMEN1KMT2AHTT | |
| SCHEMBL30276927 | 0.81 | PTPN7 (0.61) | PTPN7AGXTMEN1KMT2AHTT | |
| SCHEMBL30439679 | 0.81 | PTPN7 (0.71) | PTPN7AGXTMEN1KMT2AHTT | |
| SCHEMBL14155150 | 0.79 | PTPN7 (0.57) | PTPN7AGXTMEN1KMT2AHTT | |
| SCHEMBL12696331 | 0.78 | ALOX15 (0.56) | MEN1KMT2AHPGDRECQLALDH1A1 | |
| SCHEMBL29120010 | 0.77 | PTPN7 (0.70) | PTPN7AGXTMEN1KMT2AHTT | |
| SCHEMBL27194588 | 0.77 | PTPN7 (0.76) | PTPN7AGXTMEN1KMT2AHTT | |
| SCHEMBL6563888 | 0.76 | PTPN7 (0.73) | PTPN7AGXTMEN1KMT2AHTT | |
| SCHEMBL25640 | 0.76 | PTPN7 (1.00) | PTPN7MEN1KMT2AHTTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176776-A1 | SMALL MOLECULE INHIBITORS OF HIV-1 CAPSID ASSEMBLY | UNIVERSITY OF ALABAMA AT BIRMINGHAM (US) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176776-A1 | SMALL MOLECULE INHIBITORS OF HIV-1 CAPSID ASSEMBLY | CLINT1, ZC3HAV1, CLTC | PTPN7 1942/4885AGXT 3976/4885MEN1 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.