Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.55 |
| ▸ | BMP1 | P13497 | 2/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390559 | 1.00 | FOLH1 (0.55) | FOLH1BMP1ENPEPANPEPACE | |
| SCHEMBL30029087 | 0.97 | FOLH1 (0.52) | FOLH1BMP1ENPEPANPEPACE | |
| SCHEMBL30288024 | 0.93 | FOLH1 (0.47) | FOLH1BMP1ENPEPACEPTGS1 | |
| SCHEMBL30287991 | 0.93 | FOLH1 (0.47) | FOLH1BMP1ENPEPACEPTGS1 | |
| SCHEMBL30288015 | 0.93 | FOLH1 (0.45) | FOLH1BMP1ENPEPACEPTGS1 | |
| SCHEMBL29590961 | 0.92 | BMP1 (0.49) | FOLH1BMP1ENPEPANPEPPTGS1 | |
| SCHEMBL30390004 | 0.90 | ACE (0.46) | FOLH1BMP1ENPEPACEPTGS1 | |
| SCHEMBL30288037 | 0.90 | ACE (0.49) | FOLH1BMP1ACEPTGS1GSTK1 | |
| SCHEMBL30287995 | 0.90 | ACE (0.49) | FOLH1BMP1ACEPTGS1GSTK1 | |
| SCHEMBL31410836 | 0.89 | FOLH1 (0.49) | FOLH1BMP1RIMKLANAALAD2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9011816-B2 | Fibronectin targeting contrast agent | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-04-21 | — | — | US | disclosed |
| US-20120244070-A1 | FIBRONECTIN TARGETING CONTRAST AGENT | CASE WESTERN RESERVE UNIVERSITY | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244070-A1 | FIBRONECTIN TARGETING CONTRAST AGENT | FN1, CFD, VCAM1 | FOLH1 795/4885BMP1 298/4885ENPEP 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.