SCHEMBL33455

SCHEMBL33455

C=C(C)C(=O)OCCc1cc(C(=O)O)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.45
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 5/20 0.40
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2193856 0.91 TDP1 (0.48) THRBPOLBAPEX1HTTTDP1
SCHEMBL11519975 0.90 POLB (0.50) THRBPOLBAPEX1HTTTDP1
SCHEMBL9451047 0.85 POLB (0.33) THRBPOLBAPEX1HTTTDP1
SCHEMBL1556947 0.84 THRB (0.47) THRBPOLBAPEX1HTTTDP1
SCHEMBL4087259 0.84 THRB (0.47) THRBPOLBAPEX1HTTTDP1
SCHEMBL931727 0.84 THRB (0.47) THRBPOLBAPEX1HTTTDP1
SCHEMBL7080186 0.84 THRB (0.47) THRBPOLBAPEX1HTTTDP1
SCHEMBL33523 0.84 POLB (0.39) THRBPOLBAPEX1HTTTDP1
SCHEMBL1535487 0.84 HTT (0.57) THRBPOLBAPEX1HTTTDP1
SCHEMBL64565 0.83 THRB (0.39) THRBPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075309-A Dental resin water-gate composition, material kit, preparation method and application thereof 2026-05-26 CN claimed
WO-2026088733-A1 QUANTUM DOT BODY, QUANTUM DOT COMPOSITION, WAVELENGTH CONVERSION MATERIAL, AND PRODUCTION METHODS OF THOSE 信越化学工業株式会社 2026-04-30 WO claimed
US-12552956-B2 Photopolymerizable type dental surface coating composition SHOFU INC. (JP) 2026-02-17 US claimed
EP-4661831-A1 DENTAL VARNISH Toothshine Limited (GB) 2025-12-17 EP claimed
US-20250295625-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION SUN MEDICAL CO LTD (JP) 2025-09-25 US claimed
EP-3319581-B1 DENTAL COMPOSITIONS UNIV LONDON QUEEN MARY (GB) 2025-06-18 EP claimed
CN-119587384-A Dental ceramic prosthesis and surface modification material thereof 嘉兴市京吟生物科技有限公司 2025-03-11 CN claimed
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-12-26 US claimed
CN-119074565-A Water-based glass ion water heater and obtained tooth restoration material 深圳爱尔创口腔技术有限公司 2024-12-06 CN claimed
WO-2024164848-A1 DENTAL ADHESIVE COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF 爱迪特(秦皇岛)科技股份有限公司 2024-08-15 WO claimed
US-5264215-A Polyalkyl methacrylate and hydroxyapatite or copolymers with 4-(methacryloyloxyethyl)trimellitic acid and polymerization catalysts Nakabayashi, Nobuo (JP) 1993-11-23 US claimed
US-5264513-A Dental adhesive KABUSHIKI KAISHA SHOFU (JP) 1993-11-23 US claimed
US-5091033-A ADHESIVE FOR CERAMICS AND PROCESSES FOR THE BONDING OF CERAMICS USING SAME MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-02-25 US claimed
US-5061184-A Fluorine-containing acrylic esters; dentistry DAIKIN INDUSTRIES, LTD. (JP) 1991-10-29 US claimed
EP-0425200-A1 Bone cement composition, cured product thereof, implant material and process for the preparation of the same NOBUO NAKABAYASHI (JP) 1991-05-02 EP claimed
EP-0310919-A2 Adhesive composition for biomaterial use DAIKIN INDUSTRIES, LIMITED (JP) 1989-04-12 EP claimed
EP-0252603-A2 Adhesives for ceramics and processes for the bonding of ceramics using same MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-01-13 EP claimed
EP-0023321-B1 COMPOSITE FILLER AND DENTAL COMPOSITION CONTAINING THE SAME MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-02-06 EP claimed
EP-0023321-A2 Composite filler and dental composition containing the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-02-04 EP claimed
US-4148988-A DENTAL ADHESIVE AND UNDERVOATING FOR PAINTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1979-04-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295625-A1 AGENT FOR PROMOTING ODONTOBLAST PROPAGATION AND DIFFERENTIATION MKI67, MYADM, HGF THRB 1537/4885POLB 1686/4885APEX1 3301/4885
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS THRB 894/4885POLB 1257/4885APEX1 166/4885
US-12552956-B2 Photopolymerizable type dental surface coating composition CDH1, DCLRE1A, ITGA1 THRB 1415/4885POLB 1135/4885APEX1 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.