Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GLA | P06280 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | IL1B | P01584 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038550 | 0.86 | NPSR1 (0.54) | NPSR1HSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL2041723 | 0.85 | NPSR1 (0.56) | NPSR1HSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL12643136 | 0.84 | NPSR1 (0.49) | NPSR1HSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL12643148 | 0.84 | NPSR1 (0.51) | NPSR1HSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL2039777 | 0.82 | NPSR1 (0.52) | NPSR1HSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL2034023 | 0.78 | NPSR1 (0.57) | NPSR1HSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL2036243 | 0.77 | HTT (0.50) | NPSR1HSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL2033486 | 0.76 | MCL1 (0.52) | ALDH1A1KMT2AMEN1P2RX7IL1B | |
| SCHEMBL2039992 | 0.75 | HTT (0.48) | NPSR1HSD17B10KDM4EALDH1A1GLA | |
| SCHEMBL2035535 | 0.72 | IDO1 (0.53) | KMT2AMEN1P2RX7IL1BCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245161-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245161-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | TPSAB1, TPSB2, TPSD1 | NPSR1 49/4885HSD17B10 3797/4885KDM4E 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.