SCHEMBL1270431

SCHEMBL1270431

CC1CCC(C(C)O)CC1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.36
TRPM8 Q7Z2W7 2/20 0.36
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
EPHX1 P07099 1/20 0.30
ESR2 Q92731 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10162372 1.00 TRPA1 (0.36) TRPA1TRPM8MEN1ALDH1A1KMT2A
SCHEMBL15942196 1.00 TRPA1 (0.36) TRPA1TRPM8MEN1ALDH1A1KMT2A
SCHEMBL12696839 0.92 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL9613629 0.92 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL12002414 0.92 TRPA1 (0.32) TRPA1TRPM8
SCHEMBL127724 0.87
SCHEMBL240851 0.87 ALDH1A1 (0.36) ALDH1A1ALOX5
SCHEMBL5444346 0.87
SCHEMBL342675 0.87
SCHEMBL8183333 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO claimed
EP-2736868-B1 PROCESS FOR THE PREPARATION OF 1,4-CYCLOHEXANEDIMETHANOL EASTMAN CHEM CO (US) 2015-11-25 EP claimed
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO disclosed
CN-110724032-A Method for preparing alcohol compound by hydrogenation reduction of ketone and aldehyde 大连理工大学 2020-01-24 CN disclosed
US-10415001-B2 Derivatives of 1-(4-methylcyclohexyl)-ethanols SYMRISE AG (DE) 2019-09-17 US disclosed
US-10415001-B2 Derivatives of 1-(4-methylcyclohexyl)-ethanols SYMRISE AG (DE) 2019-09-17 US disclosed
US-9682978-B2 2,6,7 substituted purines as HDM2 inhibitors MERCK SHARP & DOHME CORP. (US) 2017-06-20 US disclosed
US-20170002294-A1 DERIVATIVES OF 1-(4-METHYLCYCLOHEXYL)-ETHANOLS SYMRISE AG (DE) 2017-01-05 US disclosed
CN-102803185-B Fuel composition comprising isoprene derivative DANISCO US INC. (US) 2016-01-06 CN disclosed
US-20150368247-A1 2,6,7 SUBSTITUTED PURINES AS HDM2 INHIBITORS MERCK SHARP & DOHME CORP. (US) 2015-12-24 US disclosed
EP-2736868-B1 PROCESS FOR THE PREPARATION OF 1,4-CYCLOHEXANEDIMETHANOL EASTMAN CHEM CO (US) 2015-11-25 EP disclosed
US-20100016532-A1 NOVEL FLUORINATED COMPOUND, FLUOROPOLYMER AND METHOD FOR PRODUCING THE COMPOUND ASAHI GLASS COMPANY, LIMITED (JP) 2010-01-21 US disclosed
US-7629468-B2 Neuroprotectants, analgesics or anticonvulsants JANSSEN PHARMACEUTICA NV (BE) 2009-12-08 US disclosed
EP-1787992-B1 Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group TAISHO PHARMACEUTICAL CO LTD (JP) 2009-04-29 EP disclosed
US-7517517-B2 Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-14 US disclosed
EP-1759212-B1 IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE 2CUREX (DK) 2008-12-17 EP disclosed
WO-2003082350-A2 RADIOLABELLED QUINOLINE AND QUINOLINONE DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR LIGANDS JANSSEN PHARMACEUTICA N.V. (BE) 2003-10-09 WO disclosed
US-4719105-A Method, compositions and compounds useful in room fresheners employing cyclohexyl alcohol and ester derivatives BUSH BOAKE ALLEN, INC. (GB) 1988-01-12 US disclosed
US-4622221-A Method, compositions and compounds, useful in room fresheners employing cyclohexyl alcohol and ester derivatives BUSH BOAKE ALLEN INC. (US) 1986-11-11 US disclosed
US-4285944-A SLEEP INDUCERS; SEDATIVES SANDOZ, INC. (US) 1981-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368247-A1 2,6,7 SUBSTITUTED PURINES AS HDM2 INHIBITORS DDX21, NSUN2, DHX29 TRPA1 4037/4885TRPM8 3532/4885MEN1 2788/4885
US-20170002294-A1 DERIVATIVES OF 1-(4-METHYLCYCLOHEXYL)-ETHANOLS OXER1, CBR3, CBR1 TRPA1 128/4885TRPM8 546/4885MEN1 2129/4885
US-20100016532-A1 NOVEL FLUORINATED COMPOUND, FLUOROPOLYMER AND METHOD FOR PRODUCING THE COMPOUND CBR3, CBR1, AFF2 TRPA1 2118/4885TRPM8 3667/4885MEN1 1161/4885
US-10415001-B2 Derivatives of 1-(4-methylcyclohexyl)-ethanols OXER1, CBR3, ADH5 TRPA1 116/4885TRPM8 503/4885MEN1 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.