Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679451 | 0.92 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL20610685 | 0.92 | ALDH1A1 (0.46) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL18545056 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL28689713 | 0.89 | SIGMAR1 (0.56) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL16749992 | 0.85 | CACNA1H (0.47) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL14642368 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL31165990 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL26869422 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL18545131 | 0.85 | CACNA1H (0.47) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL16749955 | 0.85 | CACNA1H (0.47) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919579-B2 | Imaging and therapeutic targeting of prostate and bladder tissues | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-04-05 | — | — | US | disclosed |
| US-20090123381-A1 | IMAGING AND THERAPEUTIC TARGETING OF PROSTATE AND BLADDER TISSUES | US ARMY, SECRETARY OF THE ARMY | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090123381-A1 | IMAGING AND THERAPEUTIC TARGETING OF PROSTATE AND BLADDER TISSUES | ADM2, DAB2IP, ARG2 | ALDH1A1 2563/4885TDP1 638/4885SMN1; SMN2 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.