SCHEMBL1270514

SCHEMBL1270514

C=Cc1ccc(CCC[SiH](OC)OC)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
THRB P10828 6/20 0.33
THRA P10827 5/20 0.33
CALM1 P0DP23 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 2/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2169034 0.89 ALDH1A1 (0.41) ALDH1A1THRBCHRNB2CHRNB4CHRNA3
SCHEMBL1270790 0.81 TP53 (0.40) ALDH1A1TRPA1TSHRTP53CYP4A11
SCHEMBL8759065 0.80 TDP1 (0.38) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL2199847 0.78 CYP1A2 (0.43) CALM1ALOX15
SCHEMBL734092 0.78 ALDH1A1 (0.44) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL4372159 0.77 CHRNB4 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL177912 0.77 ALDH1A1 (0.58) ALDH1A1THRBTHRACALM1MEN1
SCHEMBL1140696 0.77 ALDH1A1 (0.58) ALDH1A1THRBTHRAMEN1KMT2A
SCHEMBL10436172 0.77 ALDH1A1 (0.42) ALDH1A1THRBTHRAMEN1KMT2A
SCHEMBL17937646 0.77 TAAR1 (0.42) ALOX15HDAC8PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN claimed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
CN-110627974-A High-heat-resistance phosphorus-silicon flame retardant, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2019-12-31 CN claimed
EP-0367219-B1 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-08-31 EP claimed
US-5147947-A Graft polymer containing vinyl monomer; friction resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-09-15 US claimed
US-20250019536-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2025-01-16 US disclosed
EP-4446352-A1 WATER-BASED COATING Kaneka Corporation (JP) 2024-10-16 EP disclosed
US-20240327671-A1 WATER-BASED COATING KANEKA CORPORATION (JP) 2024-10-03 US disclosed
CN-118369388-A Water paint 株式会社钟化 2024-07-19 CN disclosed
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN disclosed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN disclosed
WO-2023190135-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION 株式会社カネカ 2023-10-05 WO disclosed
US-5250615-A Slidability; abrasion, weather, cold and impact resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-10-05 US disclosed
US-5218014-A Graft polymer formed by graft polymerization of vinyl monomer onto colloidal silica core silicone shell particles TOSHIBA SILICONE CO., LTD. (JP) 1993-06-08 US disclosed
US-5188899-A SILICA-CORE SILICONE-SHELL PARTICLES, EMULSION CONTAINING THE SAME DISPERSED THEREIN, AND PROCESS FOR PRODUCING THE EMULSION TOSHIBA SILICONE CO., LTD. (JP) 1993-02-23 US disclosed
US-5147947-A Graft polymer containing vinyl monomer; friction resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-09-15 US disclosed
EP-0433906-A2 Thermoplastic resin and process for producing the same TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0433727-A1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0367219-A2 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-05-09 EP disclosed