SCHEMBL2169034

SCHEMBL2169034

C=Cc1ccc(CC[SiH](OC)OC)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TRPA1 O75762 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TSHR P16473 2/20 0.32
TP53 P04637 2/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
THRB P10828 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1270514 0.89 ALDH1A1 (0.38) ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3
SCHEMBL2169899 0.82 ALDH1A1 (0.38) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL734092 0.81 ALDH1A1 (0.44) ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3
SCHEMBL16340911 0.79 ALDH1A1 (0.46) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL8759065 0.76 TDP1 (0.38) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL16341755 0.76 ALDH1A1 (0.42) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL1647493 0.75 ALDH1A1 (0.65) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL50012 0.75 ALDH1A1 (0.65) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL17937573 0.75 TAAR1 (0.45)
SCHEMBL6916580 0.75 SIGMAR1 (0.32) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108513626-B Dispersion, coating liquid, and heat-ray shielding film 住友大阪水泥株式会社 2020-05-19 CN disclosed
CN-105579123-B Inorganic particle dispersion, inorganic particle-containing composition, coating film, plastic substrate with coating film, and display device 住友大阪水泥股份有限公司 2020-03-13 CN disclosed
US-10472488-B2 Transparent resin composition and heat ray-shielding film SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2019-11-12 US disclosed
US-20180057655-A1 TRANSPARENT RESIN COMPOSITION AND HEAT RAY-SHIELDING FILM SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2018-03-01 US disclosed
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-8541103-B2 Silicone polymer particle and silicone composition containing same KANEKA CORPORATION (JP) 2013-09-24 US disclosed
US-7994255-B2 Polyorganiosiloxane-containing graft copolymer, resin compositions containing the same and process for produciton of polyorganosiloxane emulsions KANEKA CORPORATION (JP) 2011-08-09 US disclosed
US-7985476-B2 Transparent zirconia dispersion and zirconia particle-containing resin composition, composition for sealing light emitting element and light emitting element, hard coat film and optical functional film and optical component, and method for producing zirconia particle-containing resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2011-07-26 US disclosed
US-7776966-B2 Thermoplastic resin composition KANEKA CORPORATION (JP) 2010-08-17 US disclosed
US-7705089-B2 Rubber-modified styrene resin composition KANEKA CORPORATION (JP) 2010-04-27 US disclosed
WO-2002087523-A2 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
WO-2002088293-A1 FABRIC CARE COMPOSITIONS UNILEVER PLC (GB) 2002-11-07 WO disclosed
EP-0653447-B1 Polyorganosiloxane-type thermoplastic resin JAPAN SYNTHETIC RUBBER CO LTD (JP) 2001-06-06 EP disclosed
EP-0696621-B1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO (JP) 2000-10-11 EP disclosed
US-5939471-A COLLOIDAL SILICA DISPERSED IN RESIN MITSUBISHI RAYON CO., LTD. (JP) 1999-08-17 US disclosed
EP-0823450-A1 COMPOSITE AND MOLDINGS PRODUCED THEREFROM MITSUBISHI RAYON CO., LTD. (JP) 1998-02-11 EP disclosed
US-5695851-A CROSSLINKABLE, POLYMERIZABLE COMPOSITION CONTAINING (METH)ACRYLOYLOXY GROUPS, SILICA WHOSE SURFACE HAS BEEN MODIFIED WITH AN ORGANOSILANE-CONTAINING COMPOUND, AND A HIGH ENERGY RADIATION POLYMERIZATION INITIATOR MITSUBISHI RAYON CO., LTD. (JP) 1997-12-09 US disclosed
EP-0696621-A1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO., LTD. (JP) 1996-02-14 EP disclosed
US-5457167-A Impact strength, chemical resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-10-10 US disclosed
EP-0653447-A1 Polyorganosiloxane-type thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-05-17 EP disclosed