Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18279932 | 0.88 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL2169034 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1503461 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1270514 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL16341796 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL384789 | 0.74 | AGXT (0.43) | TP53TDP1CA1CA2MAPT | |
| SCHEMBL16340926 | 0.73 | ALDH1A1 (0.46) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL28846187 | 0.73 | ALDH1A1 (0.46) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL20537233 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL17937673 | 0.72 | IDO1 (0.41) | ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608480-B | Asymmetric silicone oil and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-02 | — | — | CN | claimed |
| WO-2022126383-A1 | ASYMMETRIC SILICONE OIL, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 万华化学集团股份有限公司 | 2022-06-23 | — | — | WO | claimed |
| CN-112608480-A | Asymmetric silicone oil and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-04-06 | — | — | CN | claimed |
| US-9884879-B2 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2018-02-06 | — | — | US | claimed |
| US-20170088565-A1 | Method of synthesizing siloxane monomers and use thereof | SILECS OY (FI) | 2017-03-30 | — | — | US | claimed |
| US-20140249326-A1 | Method of Synthesizing Siloxane Monomers and Use Thereof | SILECS OY (FI) | 2014-09-04 | — | — | US | claimed |
| WO-2012172176-A9 | METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF | SILECS OY (FI) | 2013-02-07 | — | — | WO | claimed |
| WO-2012172176-A2 | METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF | SILECS OY (FI) | 2012-12-20 | — | — | WO | claimed |
| EP-0367219-B1 | Polyorganosiloxane series thermoplastic resin and composition thereof | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1994-08-31 | — | — | EP | claimed |
| US-5250615-A | Slidability; abrasion, weather, cold and impact resistance | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1993-10-05 | — | — | US | claimed |
| US-5147947-A | Graft polymer containing vinyl monomer; friction resistance | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-09-15 | — | — | US | claimed |
| JP-2138360-A | — | — | None | — | — | JP | disclosed |
| JP-2008209-A | — | — | None | — | — | JP | disclosed |
| JP-4328149-A | — | — | None | — | — | JP | disclosed |
| JP-7331025-A | — | — | None | — | — | JP | disclosed |
| EP-0433906-A2 | Thermoplastic resin and process for producing the same | TOSHIBA SILICONE CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433727-A1 | Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion | TOSHIBA SILICONE CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |
| JP-H02138360-A | THERMOPLASTIC RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO LTD | 1990-05-28 | — | — | JP | disclosed |
| EP-0367219-A2 | Polyorganosiloxane series thermoplastic resin and composition thereof | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |
| JP-H028209-A | POLYORGANOSILOXANE THERMOPLASTIC RESIN | JAPAN SYNTHETIC RUBBER CO LTD | 1990-01-11 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088565-A1 | Method of synthesizing siloxane monomers and use thereof | MSMO1, PCNA, PIEZO1 | ALDH1A1 345/4885TRPA1 126/4885CHRNB2 3797/4885 |
| US-20140249326-A1 | Method of Synthesizing Siloxane Monomers and Use Thereof | MSMO1, PCNA, PIEZO1 | ALDH1A1 345/4885TRPA1 126/4885CHRNB2 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.