SCHEMBL12705305

SCHEMBL12705305

O=C(COC(=O)C(F)F)OCC1CCCCO1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
POLB P06746 1/20 0.55
ALDH1A1 P00352 1/20 0.52
MGLL Q99685 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12705022 0.89 LMNA (0.54) LMNAPOLBALDH1A1MGLL
SCHEMBL686296 0.79 LMNA (0.51) LMNAPOLBALDH1A1MGLL
SCHEMBL12284997 0.77 LMNA (0.59) LMNAPOLBALDH1A1MGLL
SCHEMBL12705307 0.76 LMNA (0.53) LMNAMGLL
SCHEMBL4404924 0.76 LMNA (0.48) LMNAPOLBALDH1A1MGLL
SCHEMBL1470146 0.76 LMNA (0.61) LMNAPOLBALDH1A1MGLL
SCHEMBL12018897 0.74 LMNA (0.56) LMNAPOLBALDH1A1MGLL
SCHEMBL15135511 0.74 ALDH1A1 (0.60) LMNAPOLBALDH1A1MGLL
SCHEMBL1068467 0.74 ALDH1A1 (0.87) LMNAPOLBALDH1A1MGLL
SCHEMBL27761826 0.74 LMNA (0.74) LMNAPOLBALDH1A1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110091808-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091808-A1 PHOTORESIST COMPOSITION ASIC1, ASIC3, SUN2 LMNA 3534/4885POLB 847/4885ALDH1A1 2111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.