Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12706153 | 0.86 | CES2 (0.48) | MAPTCES2P2RX1XPO1RXRA | |
| SCHEMBL5270799 | 0.79 | ALDH1A1 (0.41) | PGK1PGK2RXRARXRB | |
| SCHEMBL11815721 | 0.74 | CES2 (0.47) | NOTUMCES2P2RX1HTTRXRA | |
| SCHEMBL130017 | 0.73 | RAPGEF4 (0.50) | PGK1PGK2TAS2R14RAPGEF4MAPT | |
| SCHEMBL107119 | 0.73 | RAPGEF4 (0.56) | PGK1PGK2TAS2R14RAPGEF4MAPT | |
| SCHEMBL1825332 | 0.71 | CES2 (0.50) | MAPTCES2P2RX1MEN1HTT | |
| SCHEMBL1584197 | 0.69 | CES2 (0.48) | MAPTCES2P2RX1MEN1HTT | |
| SCHEMBL30097986 | 0.69 | CES2 (0.53) | MAPTCES2P2RX1HTTKMT2A | |
| SCHEMBL429599 | 0.69 | ALDH1A1 (0.55) | PGK1PGK2TAS2R14RAPGEF4MAPT | |
| SCHEMBL29623424 | 0.69 | ALDH1A1 (0.55) | PGK1PGK2TAS2R14RAPGEF4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311846-A1 | CHIRAL IRIDIUM AQUA COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXY COMPOUND USING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |