Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.48 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.48 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20725247 | 0.91 | CYP4F2 (0.53) | TSHRCYP4Z1TDP1PKMSMN1; SMN2 | |
| SCHEMBL31329304 | 0.85 | ALOX5 (0.55) | TSHRSMN1; SMN2LMNAALOX5MAPT | |
| SCHEMBL1613291 | 0.85 | TSHR (0.47) | TSHRCYP4Z1CYP4F11CYP4F12TDP1 | |
| SCHEMBL11091345 | 0.84 | SMN1; SMN2 (0.56) | TSHRTDP1FAAHMGLLPKM | |
| SCHEMBL10289874 | 0.82 | CYP4F2 (0.62) | CYP4Z1CYP4F11CYP4F12TDP1FAAH | |
| SCHEMBL27481392 | 0.82 | TSHR (0.51) | TSHRCYP4Z1MGLLPKMSMN1; SMN2 | |
| SCHEMBL27367107 | 0.81 | KMT2A (0.49) | TSHRCYP4Z1TDP1PKMSMN1; SMN2 | |
| SCHEMBL5708169 | 0.80 | MAPT (0.49) | TSHRTDP1PKMSMN1; SMN2MAPK1 | |
| SCHEMBL27787305 | 0.80 | SMN1; SMN2 (0.55) | TSHRTDP1FAAHMGLLPKM | |
| SCHEMBL28755965 | 0.79 | ALDH1A1 (0.50) | TSHRCYP4Z1CYP4F11CYP4F12FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078520-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | UNIVERSITY OF MISSISSIPPI | 2018-03-22 | — | — | US | disclosed |
| US-9408822-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | THE UNIVERSITY OF MISSISSIPPI (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150202176-A1 | Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis | THE UNIVERSITY OF MISSISSIPPI | 2015-07-23 | — | — | US | disclosed |
| US-9029417-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | THE UNIVERSITY OF MISSISSIPPI (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130303582-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | THE UNIVERSITY OF MISSISSIPPI | 2013-11-14 | — | — | US | disclosed |
| US-8486998-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | THE UNIVERSITY OF MISSISSIPPI (US) | 2013-07-16 | — | — | US | disclosed |
| US-20110086900-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | THE UNIVERSITY OF MISSISSIPPI | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303582-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | UGT1A3, IL33, ITCH | TSHR 4875/4885CYP4Z1 1709/4885CYP4F11 760/4885 |
| US-20150202176-A1 | Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis | UGT1A3, IL33, ITCH | TSHR 4875/4885CYP4Z1 1709/4885CYP4F11 760/4885 |
| US-20180078520-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | UGT1A3, ITCH, UGT1A1 | TSHR 4867/4885CYP4Z1 1660/4885CYP4F11 586/4885 |
| US-20110086900-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | UGT1A3, IL33, ITCH | TSHR 4875/4885CYP4Z1 1709/4885CYP4F11 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.