SCHEMBL127162

SCHEMBL127162

O=C1OC(=O)c2cc(F)c3c4c(ccc1c24)C(=O)OC3=O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYMS P04818 6/20 0.41
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.34
CDK2 P24941 2/20 0.33
TTR P02766 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPT P10636 1/20 0.30
MCL1 Q07820 1/20 0.30
PTPRC P08575 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127075 0.92 ALOX15 (0.39) TYMSALOX15TDP1ALDH1A1CDK2
SCHEMBL125844 0.90 ALOX15 (0.37) TYMSALOX15TDP1ALDH1A1
SCHEMBL127839 0.85 ALOX15 (0.33) TYMSALOX15TDP1ALDH1A1POLB
SCHEMBL127158 0.79 TYMS (0.46) TYMSALOX15TDP1ALDH1A1MEN1
SCHEMBL1188564 0.79 TYMS (0.41) TYMSALOX15TDP1ALDH1A1MEN1
SCHEMBL4324583 0.78 TYMS (0.40) TYMSALOX15TDP1ALDH1A1MEN1
SCHEMBL13784269 0.77 ALOX15 (0.40) TYMSALOX15TDP1ALDH1A1
SCHEMBL128103 0.77 TYMS (0.41) TYMSALOX15TDP1ALDH1A1MEN1
SCHEMBL13470504 0.77 TYMS (0.41) TYMSALOX15TDP1ALDH1A1MEN1
SCHEMBL148025 0.76 TYMS (0.62) TYMSALOX15TDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10741762-B2 Method for the deposition of an organic material CLAP CO., LTD. (KR) 2020-08-11 US disclosed
US-20150123090-A1 METHOD FOR THE DEPOSITION OF AN ORGANIC MATERIAL BASF SE (DE) 2015-05-07 US disclosed
US-20150123090-A1 METHOD FOR THE DEPOSITION OF AN ORGANIC MATERIAL BASF SE (DE) 2015-05-07 US disclosed
WO-2013164761-A1 METHOD FOR THE DEPOSITION OF AN ORGANIC MATERIAL BASF SE (DE) 2013-11-07 WO disclosed
EP-2532663-A1 Naphthalenecarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2012-12-12 EP disclosed
US-8309728-B2 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF AKTIENGESELLSCHAFT (DE) 2012-11-13 US disclosed
US-8309728-B2 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF AKTIENGESELLSCHAFT (DE) 2012-11-13 US disclosed
US-20120059168-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2012-03-08 US disclosed
US-20120059168-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2012-03-08 US disclosed
US-8084603-B2 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF AKTIENGESELLSCHAFT (DE) 2011-12-27 US disclosed
US-8084603-B2 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF AKTIENGESELLSCHAFT (DE) 2011-12-27 US disclosed
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors BASF SE (DE) 2008-12-04 US disclosed
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors BASF SE (DE) 2008-12-04 US disclosed
WO-2007074137-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2007-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059168-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS TST, NANS, NCDN TYMS 328/4885ALOX15 2912/4885TDP1 4130/4885
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors ADSL, ALAD, EED TYMS 173/4885ALOX15 2871/4885TDP1 4282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.