Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 19/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13926744 | 0.87 | HTR4 (0.40) | — | |
| SCHEMBL1573540 | 0.77 | CCR5 (0.44) | — | |
| SCHEMBL1573991 | 0.77 | CCR5 (0.44) | — | |
| SCHEMBL16103839 | 0.75 | OPRM1 (0.44) | — | |
| SCHEMBL27739489 | 0.71 | TP53 (0.46) | — | |
| SCHEMBL21983715 | 0.70 | CYP2A6 (0.34) | — | |
| SCHEMBL8531640 | 0.69 | HTR2A (0.43) | — | |
| SCHEMBL28754260 | 0.69 | TSHR (0.33) | — | |
| SCHEMBL27781705 | 0.68 | HTR6 (0.43) | — | |
| SCHEMBL31055045 | 0.66 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140085-B1 | AZABICYCLOALKANES AS CCR5 MODULATORS | PHIVCO UK LTD (GB) | 2011-04-13 | — | — | EP | disclosed |