SCHEMBL12721995

SCHEMBL12721995

N#Cc1ccc(N(c2ccc3c(c2)c2ccccc2n3-c2ccc(F)cc2)c2ccc3c(c2)c2cc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RORC P51449 5/20 0.36
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PGR P06401 1/20 0.34
PTGDR2 Q9Y5Y4 2/20 0.33
TP53 P04637 1/20 0.33
USP14 P54578 3/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
UBE2M P61081 1/20 0.32
DCUN1D1 Q96GG9 1/20 0.32
PTGER4 P35408 1/20 0.31
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12722017 1.00 RORC (0.36) RORCKDM4EATML3MBTL1PGR
SCHEMBL12722027 0.99 RORC (0.37) RORCKDM4EATML3MBTL1PGR
SCHEMBL12721741 0.96 PTGDR2 (0.35) RORCKDM4EPGRPTGDR2TP53
SCHEMBL13249709 0.96 PGR (0.36) RORCKDM4EPGRPTGDR2TP53
SCHEMBL12721857 0.95 PTGDR2 (0.36) RORCKDM4EPGRPTGDR2TP53
SCHEMBL12721976 0.94 RORC (0.40) RORCKDM4EATML3MBTL1USP14
SCHEMBL17463228 0.92 KDM4E (0.41) RORCKDM4EATML3MBTL1USP14
SCHEMBL12721986 0.92 KDM4E (0.41) KDM4EATML3MBTL1PTGDR2USP14
SCHEMBL12722006 0.92 KDM4E (0.41) KDM4EATML3MBTL1PTGDR2USP14
SCHEMBL12721902 0.91 PIK3CD (0.35) RORCKDM4EPGRPTGDR2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7927719-B2 Silanylamine-based compound, method of preparing the same and organic light emitting device including organic layer comprising the silanylamine-based compound SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-04-19 US disclosed
US-20080106188-A1 SILANYLAMINE-BASED COMPOUND, METHOD OF PREPARING THE SAME AND ORGANIC LIGHT EMITTING DEVICE INCLUDING ORGANIC LAYER COMPRISING THE SILANYLAMINE-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080106188-A1 SILANYLAMINE-BASED COMPOUND, METHOD OF PREPARING THE SAME AND ORGANIC LIGHT EMITTING DEVICE INCLUDING ORGANIC LAYER COMPRISING THE SILANYLAMINE-BASED COMPOUND ICMT, SLC43A1, SLC7A5 RORC 1851/4885KDM4E 2673/4885ATM 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.