Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648065 | 1.00 | ALDH1A1 (0.37) | ALDH1A1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL12411311 | 0.89 | NT5E (0.36) | ALDH1A1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL5460304 | 0.85 | PKM (0.35) | TSHRMETAP2 | |
| SCHEMBL402647 | 0.85 | PKM (0.35) | TSHRMETAP2 | |
| SCHEMBL7932128 | 0.83 | ALDH1A1 (0.38) | ALDH1A1GAABCHEABCB1L3MBTL1 | |
| SCHEMBL13024785 | 0.81 | L3MBTL1 (0.52) | ALDH1A1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL14362931 | 0.80 | METAP2 (0.37) | BCHEL3MBTL1METAP2 | |
| SCHEMBL14440540 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAABCHEABCB1L3MBTL1 | |
| SCHEMBL14440928 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAABCHEABCB1L3MBTL1 | |
| SCHEMBL14568965 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAABCHEABCB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919614-B2 | Disaccharide sequences formed by uronic acid and hexose as to form polysaccharides of 8-24 monosaccharide units whose hydroxyl groups are substituted by alkyl or sulphate groups; possible to modulate activities of glycosaminoglycans type | SANOFI-AVENTIS (FR) | 2011-04-05 | — | — | US | disclosed |