Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743427 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL195345 | 0.84 | MEN1 (0.45) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL150570 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL5512903 | 0.80 | MEN1 (0.44) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL3105615 | 0.80 | NSD2 (0.35) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL179662 | 0.79 | MEN1 (0.37) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| Sulfuric Acid SCHEMBL7805762 | 0.77 | KDM4E (0.50) | ALDH1A1HPGDMEN1KMT2ANSD2 | |
| SCHEMBL3474313 | 0.77 | MEN1 (0.33) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL127207 | 0.74 | ALDH1A1 (0.43) | ALDH1A1G6PDIDEALOX15CYP3A4 | |
| SCHEMBL3477837 | 0.74 | MEN1 (0.37) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250205370-A1 | SYNTHESIS OF TOLUIDINE BLUE O AND A KIT FOR MUCOSAL APPLICATION | PANDA SWAGATIKA (IN) | 2025-06-26 | — | — | US | claimed |
| WO-2023181060-A1 | SYNTHESIS OF TOLUIDINE BLUE O AND A KIT FOR MUCOSAL APPLICATION | PANDA SWAGATIKA (IN) | 2023-09-28 | — | — | WO | claimed |
| US-7659057-B2 | Stain-directed molecular analysis for cancer prognosis and diagnosis | ZILA BIOTECHNOLOGY, INC. (US) | 2010-02-09 | — | — | US | claimed |
| EP-1944607-A2 | Toluidine blue O compounds and their manufacture, analysis and use | Zila, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| CN-1188173-C | Vivo stain composition, process of manufacture, methods of use to identify dysplastic tissue | ZILA INC (US) | 2005-02-09 | — | — | CN | claimed |
| US-20020111501-A1 | Process for manufacture of in vivo stain composition | BURKETT DOUGLAS D (US) | 2002-08-15 | — | — | US | claimed |
| US-6372904-B2 | OXIDIZING N,N'-DIMETHYL-P-PHENYLENE DIAMINE IN FIRST REACTION MIXTURE, INTRODUCING SODIUM THIOSULFATE IONS TO FORM 2-AMINO-5-DIMETHYLAMINOPHENYL THIOSULFONIC ACID, OXIDING THE INTERMEDIATE WITH O-TOLUDINE TO FORM SECOND INTERMEDIATE | ZILA, INC. | 2002-04-16 | — | — | US | claimed |
| US-20010007904-A1 | Process for manufacture of in vivo stain composition | MIDCAP FUNDING V, LLC, AS ADMINISTRATIVE AGENT | 2001-07-12 | — | — | US | claimed |
| US-6086852-A | CONFORMATIONAL ISOMERS OF TOLUIDINE BLUE O, AND N-DEMETHYLATION DERIVATIVES; SYNTHESIS, IN WHICH A COMPLEXING AGENT IS INTRODUCED PRIOR TO THE LAST STAGE OF OXIDATION OF A THREE-STEP SYNTHESIS FROM N,N-DIMETHYL-P-PHENYLENEDIAMINE | ZILA, INC. (US) | 2000-07-11 | — | — | US | claimed |
| EP-0966957-A2 | In vivo stain composition, process of manufacture, and methods of use to identify dysplastic tissue | Zila Inc. (US) | 1999-12-29 | — | — | EP | claimed |
| CN-1225278-A | In vivo staining composition, method for preparing the same and method for identifying dysplastic tissue | ZILA INC (US) | 1999-08-11 | — | — | CN | claimed |
| WO-1999025388-A1 | IN VIVO STAIN COMPOSITION, PROCESS OF MANUFACTURE, AND METHODS OF USE TO IDENTIFY DYSPLASTIC TISSUE | ZILA, INC. (US) | 1999-05-27 | — | — | WO | claimed |
| US-4212971-A | Process for preparing methylene blue | AMERICAN CYANAMID COMPANY (US) | 1980-07-15 | — | — | US | claimed |
| JP-11209357-A | — | — | None | — | — | JP | disclosed |
| US-20250205370-A1 | SYNTHESIS OF TOLUIDINE BLUE O AND A KIT FOR MUCOSAL APPLICATION | PANDA SWAGATIKA (IN) | 2025-06-26 | — | — | US | disclosed |
| WO-2025082959-A1 | A PHENOTHIAZINE-RELATED COMPOUND CONJUGATED TO A PEPTIDE | UNIVERSITY OF ULSTER (GB) | 2025-04-24 | — | — | WO | disclosed |
| US-5532171-A | PHENOTHIAZINE DYES FOR PHOTODYNAMIC THERAPY OF CANCER OR IMMUNOASSAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5344928-A | Phenothiazine compounds for cancer treatment or immunoassay using chemiluminescence | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0510668-A2 | Phenothiazine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |
| US-4212971-A | Process for preparing methylene blue | AMERICAN CYANAMID COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250205370-A1 | SYNTHESIS OF TOLUIDINE BLUE O AND A KIT FOR MUCOSAL APPLICATION | KIT, MKI67, KDM5B | ALDH1A1 177/4885HPGD 1547/4885MEN1 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.