Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190887 | 0.82 | ALDH1A1 (0.41) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL14355932 | 0.81 | MAPT (0.49) | ALDH1A1ALOX15TDP1APPKDM4E | |
| SCHEMBL10631846 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL22753827 | 0.76 | NPC1 (0.44) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL22753824 | 0.76 | NPC1 (0.44) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL5165904 | 0.75 | CASP1 (0.44) | ALDH1A1ALOX15CYP3A4TDP1TP53 | |
| SCHEMBL2313495 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL31361979 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL743427 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 | |
| SCHEMBL127303 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15CYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691979-B2 | Methods of chemical synthesis of diaminophenothiazinium compounds involving the use of persulfate oxidants | WISTA LABORATORIES LTD. (SG) | 2014-04-08 | — | — | US | disclosed |
| US-20120058995-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | WISTA LABORATORIES LTD. (SG) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058995-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | TST, TPMT, MGMT | ALDH1A1 748/4885ALOX15 2129/4885CYP3A4 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.