Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127303 | 0.80 | ALDH1A1 (0.39) | NSD2G6PDIDEHDAC1CA2 | |
| SCHEMBL743427 | 0.80 | ALDH1A1 (0.39) | NSD2G6PDIDEHDAC1CA2 | |
| Sulfuric Acid SCHEMBL7805762 | 0.73 | KDM4E (0.50) | NSD2HDAC1CA2KDM4ECA1 | |
| SCHEMBL127207 | 0.71 | ALDH1A1 (0.43) | G6PDIDEHDAC1KDM4EALDH1A1 | |
| SCHEMBL11551865 | 0.70 | NSD2 (0.47) | NSD2HDAC1CA2KDM4ECA1 | |
| Sulfuric Acid SCHEMBL8535837 | 0.70 | ALDH1A1 (0.49) | CA2KDM4ECA1ALDH1A1CYP3A4 | |
| SCHEMBL190887 | 0.70 | ALDH1A1 (0.41) | G6PDIDEHDAC1KDM4EALDH1A1 | |
| SCHEMBL743428 | 0.68 | NSD2 (0.42) | NSD2HDAC1CA2KDM4ECA1 | |
| SCHEMBL151025 | 0.68 | NSD2 (0.42) | NSD2HDAC1CA2KDM4ECA1 | |
| SCHEMBL30612673 | 0.68 | NSD2 (0.42) | NSD2HDAC1CA2KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447421-A | Synthesis method of 3, 7-bis- (dimethylamino) -phenothiazine | 上海沃凯生物技术有限公司 | 2024-01-26 | — | — | CN | disclosed |
| WO-2010118050-A1 | USE OF IMPROVED TOLUIDINE BLUE IN PHOTODYNAMIC THERAPY | ZILA, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100256125-A1 | USE OF IMPROVED TOLUIDINE BLUE IN PHOTODYNAMIC THERAPY | ZILA PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| CN-1302815-C | Toluidine blue O drug substance and use thereof for in VIVO Staining and chemo therapeutic treatment of dysplastic tissues | ZILA BIOTECH INC (US) | 2007-03-07 | — | — | CN | disclosed |
| CN-1627961-A | Toluidine blue O drug substance and use thereof for in VIVO Staining and chemo therapeutic treatment of dysplastic tissues | ZILA BIOTECH INC (US) | 2005-06-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256125-A1 | USE OF IMPROVED TOLUIDINE BLUE IN PHOTODYNAMIC THERAPY | TET1, KDM2B, KDM5B | NSD2 53/4885G6PD 84/4885IDE 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.