Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127303 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL195345 | 0.84 | MEN1 (0.45) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL150570 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL5512903 | 0.80 | MEN1 (0.44) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL3105615 | 0.80 | NSD2 (0.35) | ALDH1A1HPGDMEN1KMT2AL3MBTL1 | |
| SCHEMBL179662 | 0.79 | MEN1 (0.37) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| Sulfuric Acid SCHEMBL7805762 | 0.77 | KDM4E (0.50) | ALDH1A1HPGDMEN1KMT2ANSD2 | |
| SCHEMBL3474313 | 0.77 | MEN1 (0.33) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 | |
| SCHEMBL127207 | 0.74 | ALDH1A1 (0.43) | ALDH1A1G6PDIDEALOX15CYP3A4 | |
| SCHEMBL3477837 | 0.74 | MEN1 (0.37) | ALDH1A1HPGDMEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430007-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | Wista Laboratories Ltd. (SG) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130977-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | WISTA LABORATORIES LTD. (SG) | 2010-11-18 | — | — | WO | disclosed |