Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.39 |
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSB | P07858 | 5/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273048 | 1.00 | CTSL (0.39) | CTSLCTSSCTSKCTSBFOLH1 | |
| SCHEMBL12243756 | 0.92 | CTSL (0.46) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL13584738 | 0.92 | CTSL (0.46) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL2377785 | 0.92 | CTSL (0.46) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL2820139 | 0.92 | CTSL (0.46) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL1273044 | 0.82 | CTSS (0.62) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2401298 | 0.80 | CTSL (0.37) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL1272534 | 0.78 | CTSL (0.35) | CTSLCTSSCTSKCTSBFOLH1 | |
| SCHEMBL1272535 | 0.78 | CTSL (0.35) | CTSLCTSSCTSKCTSBFOLH1 | |
| SCHEMBL1272478 | 0.77 | CTSL (0.44) | CTSLCTSSCTSKCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893093-B2 | Sulfonyl containing compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20080287446-A1 | Sulfonyl Containing Compounds as Cysteine Protease Inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287446-A1 | Sulfonyl Containing Compounds as Cysteine Protease Inhibitors | CTSS, CTSF, CTSB | CTSL 10/4885CTSS 1/4885CTSK 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.