Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734550 | 0.89 | KDM4E (0.46) | TNFKDM4EALDH1A1HPGDPARP1 | |
| SCHEMBL12731968 | 0.85 | CCR1 (0.43) | TNFKDM4EMAPTPARP1MET | |
| SCHEMBL12731984 | 0.84 | LMNA (0.43) | MAPK10KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL12731981 | 0.83 | KDM4E (0.46) | KDM4EMAPTPARP1CYP2A6 | |
| SCHEMBL12731988 | 0.79 | CCR1 (0.39) | TNFKDM4EMAPTALDH1A1PARP1 | |
| SCHEMBL2734566 | 0.78 | TNF (0.45) | TNFKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL2734767 | 0.78 | BIRC5 (0.47) | PIK3CDPIK3CBPIK3CGMETCYP2A6 | |
| SCHEMBL12731980 | 0.77 | L3MBTL1 (0.40) | TNFMAPTALDH1A1METDYRK1A | |
| SCHEMBL251545 | 0.77 | CYP11B1 (0.48) | TNFKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL12731985 | 0.76 | IDO1 (0.39) | TNFKDM4EMAPTTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7931975-B2 | Electroluminescent device containing a flouranthene compound | GLOBAL OLED TECHNOLOGY LLC (US) | 2011-04-26 | — | — | US | disclosed |
| US-7931975-B2 | Electroluminescent device containing a flouranthene compound | GLOBAL OLED TECHNOLOGY LLC (US) | 2011-04-26 | — | — | US | disclosed |
| US-20100117519-A1 | ELECTROLUMINESCENT DEVICE CONTAINING A FLOURANTHENE COMPOUND | GLOBAL OLED TECHNOLOGY LLC | 2010-05-13 | — | — | US | disclosed |
| US-20100117519-A1 | ELECTROLUMINESCENT DEVICE CONTAINING A FLOURANTHENE COMPOUND | GLOBAL OLED TECHNOLOGY LLC | 2010-05-13 | — | — | US | disclosed |