Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 5/20 | 0.37 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733305 | 0.86 | NQO2 (0.33) | NQO2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL12733302 | 0.82 | HDAC6 (0.33) | NQO2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL20468810 | 0.81 | NQO2 (0.35) | NQO2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL18291043 | 0.77 | ALDH1A1 (0.46) | CYP3A4CYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL12733298 | 0.75 | KDM4E (0.33) | ALDH1A1KMT2AKDM4EHSD17B10MAPT | |
| SCHEMBL10082369 | 0.71 | MPL (0.43) | CYP3A4CYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL1673086 | 0.71 | CDC25A (0.43) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL22502968 | 0.71 | NQO2 (0.32) | NQO2CYP1A2 | |
| SCHEMBL17803468 | 0.71 | HDAC3 (0.36) | NQO2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL9152694 | 0.70 | RAPGEF4 (0.55) | KAT2BNQO2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658434-B2 | Fluorescent pyrene compounds | BIOTIUM, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-20110097735-A1 | FLUORESCENT PYRENE COMPOUNDS | BIOTIUM, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097735-A1 | FLUORESCENT PYRENE COMPOUNDS | PAH, CYP1A1, PYCR1 | KAT2B 3897/4885FERMT2 1265/4885NQO2 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.