Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886217 | 0.82 | CDC25A (0.41) | CDC25ACDC25BALDH1A1MEN1KMT2A | |
| SCHEMBL22502968 | 0.81 | NQO2 (0.32) | — | |
| SCHEMBL17812420 | 0.78 | HDAC3 (0.33) | ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL20468810 | 0.78 | NQO2 (0.35) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL22562309 | 0.78 | GRIN1 (0.32) | ALDH1A1MAPTKDM4ELMNAHSD17B10 | |
| SCHEMBL1672444 | 0.77 | ALB (0.40) | ALDH1A1TBXA2RFABP4 | |
| SCHEMBL17812419 | 0.76 | HDAC3 (0.32) | — | |
| SCHEMBL17119894 | 0.71 | KMT2A (0.57) | CDC25ACDC25BALDH1A1MEN1KMT2A | |
| SCHEMBL12733301 | 0.71 | KAT2B (0.37) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL1502343 | 0.70 | CYP1A2 (0.43) | ALDH1A1MEN1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227264-B1 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | LIFE TECHNOLOGIES CORP (US) | 2020-10-21 | — | — | EP | disclosed |
| EP-3227264-B1 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | LIFE TECHNOLOGIES CORP (US) | 2020-10-21 | — | — | EP | disclosed |
| US-10793518-B2 | Hydrazinyl and aminooxy compounds and their methods of use | Life Technologies Corporation (US) | 2020-10-06 | — | — | US | disclosed |
| US-10793518-B2 | Hydrazinyl and aminooxy compounds and their methods of use | Life Technologies Corporation (US) | 2020-10-06 | — | — | US | disclosed |
| US-10246410-B2 | Hydrazinyl and aminooxy compounds and their methods of use | Life Technologies Corporation (US) | 2019-04-02 | — | — | US | disclosed |
| US-10246410-B2 | Hydrazinyl and aminooxy compounds and their methods of use | Life Technologies Corporation (US) | 2019-04-02 | — | — | US | disclosed |
| US-20180222855-A1 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | Life Technologies Corporation | 2018-08-09 | — | — | US | disclosed |
| US-20180222855-A1 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | Life Technologies Corporation | 2018-08-09 | — | — | US | disclosed |
| US-20170369431-A1 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | Life Technologies Corporation | 2017-12-28 | — | — | US | disclosed |
| EP-3227264-A2 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | Life Technologies Corporation (US) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016090076-A2 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | Life Technologies Corporation (US) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016090076-A2 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | Life Technologies Corporation (US) | 2016-06-09 | — | — | WO | disclosed |
| US-8658434-B2 | Fluorescent pyrene compounds | BIOTIUM, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-20110097735-A1 | FLUORESCENT PYRENE COMPOUNDS | BIOTIUM, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793518-B2 | Hydrazinyl and aminooxy compounds and their methods of use | PHYKPL, AASDHPPT, CA14 | CDC25A 2882/4885CDC25B 2557/4885ALDH1A1 393/4885 |
| US-20110097735-A1 | FLUORESCENT PYRENE COMPOUNDS | PAH, CYP1A1, PYCR1 | CDC25A 2609/4885CDC25B 2091/4885ALDH1A1 845/4885 |
| US-10246410-B2 | Hydrazinyl and aminooxy compounds and their methods of use | PHYKPL, AASDHPPT, CA14 | CDC25A 2882/4885CDC25B 2557/4885ALDH1A1 393/4885 |
| US-20170369431-A1 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | PHYKPL, AASDHPPT, CA14 | CDC25A 2882/4885CDC25B 2557/4885ALDH1A1 393/4885 |
| US-20180222855-A1 | HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE | PHYKPL, AASDHPPT, CA14 | CDC25A 2882/4885CDC25B 2557/4885ALDH1A1 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.