Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TK2 | O00142 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733981 | 0.88 | TYMS (0.43) | — | |
| SCHEMBL9211927 | 0.87 | TK1 (0.50) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL9211924 | 0.87 | TK1 (0.50) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL12806692 | 0.81 | TK1 (0.47) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL13166488 | 0.79 | TK1 (0.49) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL12733980 | 0.78 | RNASE1 (0.34) | TK1 | |
| SCHEMBL29384119 | 0.78 | TK1 (0.53) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL29676843 | 0.78 | TK1 (0.53) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL9211446 | 0.75 | LMNA (0.45) | TK1LMNASMN1; SMN2 | |
| SCHEMBL9211454 | 0.75 | LMNA (0.45) | TK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092382-A1 | Modified Nucleic Acid Probes | AFFYMETRIX, INC. (US) | 2011-04-21 | — | — | US | disclosed |