Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211446 | 1.00 | LMNA (0.45) | LMNASMN1; SMN2PNPTP53HTT | |
| SCHEMBL1795053 | 0.82 | PNP (0.46) | LMNASMN1; SMN2PNPTP53HTT | |
| SCHEMBL20691354 | 0.75 | HIF1A (0.52) | LMNASMN1; SMN2PNPTP53HTT | |
| SCHEMBL12733983 | 0.75 | TK1 (0.50) | LMNASMN1; SMN2TK1 | |
| SCHEMBL9211924 | 0.75 | TK1 (0.50) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL9211927 | 0.75 | TK1 (0.50) | LMNASMN1; SMN2ADRB1DNMT1TK1 | |
| SCHEMBL6439746 | 0.75 | ADORA2A (0.47) | PDE4DPDE3A | |
| SCHEMBL23982125 | 0.74 | ADRB1 (0.47) | LMNASMN1; SMN2PNPTP53HTT | |
| SCHEMBL22333925 | 0.74 | ADRB1 (0.47) | LMNASMN1; SMN2PNPTP53HTT | |
| SCHEMBL22334012 | 0.74 | ADRB1 (0.47) | LMNASMN1; SMN2PNPTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286028-B1 | Derivatives of disazapurine nucleosides, process for their preparation and their use in the sequence analysis of nucleic acids and as antiviral agents | BOEHRINGER MANNHEIM GMBH (DE) | 1995-06-28 | — | — | EP | claimed |
| EP-0286028-B1 | Derivatives of disazapurine nucleosides, process for their preparation and their use in the sequence analysis of nucleic acids and as antiviral agents | BOEHRINGER MANNHEIM GMBH (DE) | 1995-06-28 | — | — | EP | disclosed |