SCHEMBL12735262

SCHEMBL12735262

CCCCCC1CCC(c2ccc(CCc3ccc(-c4ccc(OC)c(F)c4F)cc3)c(F)c2F)CC1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 4/20 0.34
LYPLA1 O75608 1/20 0.32
LYPLA2 O95372 1/20 0.32
ABHD16A O95870 1/20 0.32
FPR2 P25090 2/20 0.31
TRPV1 Q8NER1 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12739946 1.00 FFAR4 (0.34) FFAR4LYPLA1LYPLA2ABHD16AFPR2
SCHEMBL12735071 0.93 FFAR4 (0.36) FFAR4
SCHEMBL12735271 0.93 FFAR4 (0.35) FFAR4
SCHEMBL12739952 0.93 FFAR4 (0.35) FFAR4
SCHEMBL12739803 0.93 FFAR4 (0.36) FFAR4
SCHEMBL8934938 0.90 FPR2 (0.36) FPR2ALOX5APFEN1
SCHEMBL12739945 0.89 FFAR4 (0.35) FFAR4FPR2ALOX5APFEN1
SCHEMBL12735259 0.89 FFAR4 (0.35) FFAR4FPR2ALOX5APFEN1
SCHEMBL8935029 0.89 GAA (0.36) LYPLA1LYPLA2ABHD16AFPR2TRPV1
SCHEMBL12739990 0.88 LYPLA1 (0.36) FFAR4LYPLA1LYPLA2ABHD16ATRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE LEF1, LAS1L, EFHD2 FFAR4 546/4885LYPLA1 751/4885LYPLA2 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.