Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.69 |
| ▸ | HLCS | P50747 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ABL1 | P00519 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | IDE | P14735 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA9 | Q16790 | 3/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.62 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036929 | 1.00 | TDP1 (0.69) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL24179756 | 1.00 | TDP1 (0.69) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL22560803 | 1.00 | TDP1 (0.69) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL26551954 | 1.00 | TDP1 (0.69) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL10063351 | 1.00 | TDP1 (0.69) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL17881931 | 0.97 | TDP1 (0.71) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL16923825 | 0.97 | TDP1 (0.71) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL13166618 | 0.96 | TDP1 (0.64) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL17128734 | 0.94 | TDP1 (0.67) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL12085208 | 0.94 | TDP1 (0.70) | TDP1HLCSPKMMEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11660290-B2 | Affinity based drug release formulations | MCMASTER UNIVERSITY (CA) | 2023-05-30 | — | — | US | disclosed |
| WO-2023018743-A1 | PH-RESPONSIVE NANOPARTICLE FOR DELIVERY OF RIBONUCLEOPROTEINS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2020246602-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | 大塚製薬株式会社 | 2020-12-10 | — | — | WO | disclosed |
| US-10787465-B2 | Lanthanide toolbox for organelle specific molecular imaging with multi-color | NEW LIFE MEDICINE TECHNOLOGY COMPANY LIMITED (CN) | 2020-09-29 | — | — | US | disclosed |
| US-20170368033-A1 | AFFINITY BASED DRUG RELEASE FORMULATIONS | MCMASTER UNIVERSITY (CA) | 2017-12-28 | — | — | US | disclosed |
| WO-2017060729-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LIMITED (GB) | 2017-04-13 | — | — | WO | disclosed |
| US-9290421-B2 | Hypervalent radioactive astatine or iodine compounds, and preparation methods thereof | Institut National de la Santé de la Recherche Medicalé (FR) | 2016-03-22 | — | — | US | disclosed |
| US-7932213-B2 | Solid phase synthesis with benzylidene linker attaching compound on glass slide; microarrays; drug screening | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-04-26 | — | — | US | disclosed |
| US-20070161007-A1 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-12 | — | — | US | disclosed |
| US-20070161007-A1 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170368033-A1 | AFFINITY BASED DRUG RELEASE FORMULATIONS | ABCG2, ABCB1, ABCB11 | TDP1 2465/4885HLCS 317/4885PKM 3166/4885 |
| US-10787465-B2 | Lanthanide toolbox for organelle specific molecular imaging with multi-color | DYNC1LI2, DYNLL2, DYNLL1 | TDP1 2091/4885HLCS 408/4885PKM 2960/4885 |
| US-11660290-B2 | Affinity based drug release formulations | ABCG2, ABCB1, ABCB11 | TDP1 2465/4885HLCS 317/4885PKM 3166/4885 |
| US-20070161007-A1 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | DNMT1, MAT2A, MAT1A | TDP1 931/4885HLCS 689/4885PKM 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.