SCHEMBL1273741

SCHEMBL1273741

CCCNC(=N)NCCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40
EPHX1 P07099 5/20 0.39
MCL1 Q07820 1/20 0.37
KDM4C Q9H3R0 1/20 0.34
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PAOX Q6QHF9 1/20 0.32
ADH1B P00325 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30
CA1 P00915 1/20 0.30
EPHX2 P34913 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
CHRNB2 P17787 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13973081 0.91
SCHEMBL16309335 0.89 EPHX1 (0.48) MMP1MMP2EPHX1KMT2A
SCHEMBL13943361 0.88 MMP1 (0.37) MMP1MMP2MMP3MMP9EPHX1
SCHEMBL17046805 0.87 EPHX1 (0.58) EPHX1ALDH1A1PAOX
SCHEMBL349059 0.87 MMP1 (0.33) MMP1MMP2MMP3MMP9EPHX1
SCHEMBL4100814 0.85
SCHEMBL564253 0.85
SCHEMBL15228190 0.83
SCHEMBL10446327 0.83
SCHEMBL26760772 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220169815-A1 GAS GENERATING AGENT, FOAMABLE COMPOSITION, FOAM, AND METHOD OF PRODUCING FOAM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-06-02 US disclosed
US-10077336-B2 Functionalized highly branched melamine-polyamine polymers BASF SE (DE) 2018-09-18 US disclosed
EP-2545123-B1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2018-05-16 EP disclosed
US-8911929-B2 Developer and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-12-16 US disclosed
US-8911929-B2 Developer and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-12-16 US disclosed
US-20140141377-A1 DEVELOPER AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-22 US disclosed
US-20140141377-A1 DEVELOPER AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-22 US disclosed
US-8466221-B2 Polyamides that resist heat-aging BASF SE (DE) 2013-06-18 US disclosed
EP-2545123-A1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2013-01-16 EP disclosed
EP-2513201-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS BASF SE (DE) 2012-10-24 EP disclosed
US-20050129645-A1 Hair shaping composition comprising at least one non-hydroxide imine L'OREAL 2005-06-16 US disclosed
EP-1532963-A1 Composition for straightening the hair comprising at least one imine not being an hydroxide L'OREAL (FR) 2005-05-25 EP disclosed
EP-1532960-A1 Hair styling composition containing a non-hydroxide imine L'OREAL (FR) 2005-05-25 EP disclosed
US-6825191-B2 ANTICOAGULANT AJINOMOTO CO., INC. (JP) 2004-11-30 US disclosed
US-6667356-B2 Including an n-amidinobenzamide derivative; heat aging resistance BRIDGESTONE CORPORATION (JP) 2003-12-23 US disclosed
US-20030186969-A1 Benzodiazepine derivatives AJINOMOTO CO. INC (JP) 2003-10-02 US disclosed
EP-1329450-A1 BENZODIAZEPINE DERIVATIVE Ajinomoto Co., Inc. (JP) 2003-07-23 EP disclosed
US-20030134947-A1 Containing imine, amidine or guanidine antioxidants to improve heat aging resistance; may be substituted by acyl, thioacyl or additional imine groups BRIDGESTONE CORPORATION, OTSUKA CHEMICAL CO., LTD. 2003-07-17 US disclosed
US-6515055-B1 Excellent in heat aging resistance due to addition of compounds exemplified by N'-(N-benzoylamidino) benzoic acid hydrazide BRIDGESTONE CORPORATION (JP) 2003-02-04 US disclosed
EP-1101793-A1 Heat ageing resistant rubber composition Bridgestone Corporation (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186969-A1 Benzodiazepine derivatives GABRA1, F11, GABRA4 MMP1 2960/4885MMP2 1686/4885MMP3 1419/4885
US-20050129645-A1 Hair shaping composition comprising at least one non-hydroxide imine KRT18, INHA, H1-5 MMP1 158/4885MMP2 1269/4885MMP3 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.