Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273899 | 0.78 | SRC (0.42) | MEN1KMT2ACNR2ACLYPPARG | |
| SCHEMBL28332952 | 0.76 | SRC (0.48) | MEN1KMT2AACLYPPARGALDH1A1 | |
| SCHEMBL28328822 | 0.75 | CES2 (0.43) | CES2CES1MEN1KMT2ACNR2 | |
| SCHEMBL28436668 | 0.73 | MEN1 (0.40) | MEN1KMT2ARAB9A | |
| SCHEMBL21061039 | 0.73 | CA1 (0.36) | KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL1274762 | 0.71 | ALDH1A1 (0.56) | CES2CES1MEN1KMT2ACNR2 | |
| SCHEMBL30059683 | 0.71 | ALDH1A1 (0.56) | CES2CES1MEN1KMT2ACNR2 | |
| SCHEMBL3578523 | 0.71 | MAPK1 (0.39) | MEN1KMT2AALDH1A1TDP1CTSA | |
| SCHEMBL19892726 | 0.70 | L3MBTL1 (0.40) | MEN1KMT2ACNR2RAB9ALMNA | |
| SCHEMBL12477325 | 0.70 | CES2 (0.47) | CES2MEN1KMT2APPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462124-B9 | MESOIONIC PESTICIDES | DU PONT (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9596856-B2 | Mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20160066577-A1 | MESOIONIC PESTICIDES | FMC CORPORATION | 2016-03-10 | — | — | US | disclosed |
| US-9210932-B2 | Mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-12-15 | — | — | US | disclosed |
| EP-2679583-B1 | Mesoionic pesticides | DU PONT (US) | 2015-06-17 | — | — | EP | disclosed |
| US-20140206536-A1 | MESOIONIC PESTICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-24 | — | — | US | disclosed |
| US-8722690-B2 | Mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2462124-B1 | MESOIONIC PESTICIDES | DU PONT (US) | 2014-01-08 | — | — | EP | disclosed |
| US-20120277100-A1 | MESOIONIC PESTICIDES | FMC CORPORATION | 2012-11-01 | — | — | US | disclosed |
| EP-2462124-A2 | MESOIONIC PESTICIDES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017342-A2 | MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206536-A1 | MESOIONIC PESTICIDES | CHRM3, CHRM2, CHRM5 | CES2 738/4885CES1 977/4885MEN1 920/4885 |
| US-20160066577-A1 | MESOIONIC PESTICIDES | CHRM3, CHRM2, CHRM5 | CES2 738/4885CES1 977/4885MEN1 920/4885 |
| US-20120277100-A1 | MESOIONIC PESTICIDES | CHRM3, CHRM2, CHRM5 | CES2 732/4885CES1 969/4885MEN1 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.