Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327522 | 0.94 | PPARG (0.47) | CES2PPARGACP3PNMTLMNA | |
| SCHEMBL2687361 | 0.86 | RORB (0.39) | CES2PPARGSTK39 | |
| SCHEMBL28436668 | 0.83 | MEN1 (0.40) | ACP3MEN1KMT2A | |
| SCHEMBL28341288 | 0.83 | PPARG (0.54) | CES2PPARGACP3PNMTLMNA | |
| SCHEMBL28328822 | 0.82 | CES2 (0.43) | CES2PPARGMEN1CYP1A2CYP3A4 | |
| SCHEMBL15671624 | 0.82 | P2RX1 (0.40) | CNR1 | |
| SCHEMBL28732508 | 0.82 | MAPK1 (0.35) | PPARGMEN1KMT2A | |
| SCHEMBL1273899 | 0.80 | SRC (0.42) | PPARGSTK39ALDH1A1MEN1KMT2A | |
| SCHEMBL19892726 | 0.80 | L3MBTL1 (0.40) | ACP3LMNAHPGDMEN1KMT2A | |
| SCHEMBL28444437 | 0.78 | ACP3 (0.51) | CES2PPARGACP3PNMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574194-B | Pyrimidine salt compound synthesis and application | 东莞市东阳光农药研发有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-112851665-B | Novel mesoionic compounds and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-114369090-A | Mesoionic compound and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-113968854-A | Novel onium salt compound and synthesis and application thereof | 东莞市东阳光农药研发有限公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-113563327-A | Novel mesoionic compound and synthesis and application thereof | 东莞市东阳光农药研发有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-112851665-A | Novel mesoionic compounds and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-112574194-A | Synthesis and application of pyrimidinium salt compound | 东莞市东阳光农药研发有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-110317200-B | Pyrimidinium compounds and uses thereof | 东莞市东阳光农药研发有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-110452238-B | Pyrimidinium compounds and uses thereof | 东莞市东阳光农药研发有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-107531700-B | Mesoionic compounds | 日本化药株式会社 | 2020-03-03 | — | — | CN | disclosed |
| EP-3287457-B1 | MESOIONIC COMPOUND | NIPPON KAYAKU KK (JP) | 2019-09-18 | — | — | EP | disclosed |
| EP-3521287-A1 | NOVEL MESOIONIC INSECTICIDAL COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-20180310564-A1 | Mesoionic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2018-11-01 | — | — | US | disclosed |
| EP-3287457-A1 | MESOIONIC COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2018-02-28 | — | — | EP | disclosed |
| EP-2658856-B1 | MESOIONIC PYRIDO [1,2-A] PYRIMIDINE PESTICIDES | DU PONT (US) | 2015-02-25 | — | — | EP | disclosed |
| US-20150038329-A1 | MESOIONIC PESTICIDES | DU PONT (US) | 2015-02-05 | — | — | US | disclosed |
| US-8895738-B2 | Mesoionic pyrido [1, 2-A] pyrimidine pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-25 | — | — | US | disclosed |
| EP-2658856-A1 | MESOIONIC PYRIDO [1,2 -A]PYRIMIDINE PESTICIDES | E.I. Du Pont De Nemours And Company (US) | 2013-11-06 | — | — | EP | disclosed |
| US-20130190171-A1 | MESOIONIC PYRIDO [1, 2-A] PYRIMIDINE PESTICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-25 | — | — | US | disclosed |
| WO-2012092115-A1 | MESOIONIC PYRIDO [1,2 -A] PYRIMIDINE PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038329-A1 | MESOIONIC PESTICIDES | C5, DDT, CBR3 | CES2 304/4885PPARG 4492/4885ACP3 3048/4885 |
| US-20130190171-A1 | MESOIONIC PYRIDO [1, 2-A] PYRIMIDINE PESTICIDES | PNPO, C5, CBR3 | CES2 639/4885PPARG 4409/4885ACP3 3653/4885 |
| US-20180310564-A1 | Mesoionic Compound | MTX1, METTL3, MTX2 | CES2 1287/4885PPARG 1939/4885ACP3 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.