Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.75 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.75 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29784945 | 0.83 | CHRNB2 (1.00) | CHRNB2CHRNA4 | |
| SCHEMBL12827198 | 0.83 | CHRNB2 (1.00) | CHRNB2CHRNA4 | |
| SCHEMBL22831347 | 0.83 | CHRNB2 (0.87) | CHRNB2CHRNA4 | |
| SCHEMBL12744959 | 0.80 | LTA4H (0.58) | CHRNB2CHRNA4KCNH2 | |
| SCHEMBL7105377 | 0.79 | CHRNB2 (0.84) | CHRNB2CHRNA4 | |
| SCHEMBL7101849 | 0.78 | CHRNB2 (0.81) | CHRNB2CHRNA4 | |
| SCHEMBL11894508 | 0.77 | CHRNB2 (0.64) | CHRNB2CHRNA4 | |
| SCHEMBL30338591 | 0.74 | CHRNB2 (0.68) | CHRNB2CHRNA4 | |
| SCHEMBL171896 | 0.74 | CHRNB2 (0.68) | CHRNB2CHRNA4 | |
| SCHEMBL14396218 | 0.74 | CHRNB2 (0.60) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071289-A1 | AMINOPYRAZOLE AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071289-A1 | AMINOPYRAZOLE AMIDE DERIVATIVE | ARGLU1, ARG1, CNKSR1 | CHRNB2 4797/4885CHRNA4 4555/4885GBA1 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.