Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187928 | 0.83 | AGTR1 (0.50) | AGTR1AGTR2SMN1; SMN2ALDH1A1HTR2C | |
| SCHEMBL5966721 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL13232458 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2SMN1; SMN2HIF1ANPSR1 | |
| SCHEMBL20429121 | 0.82 | AGTR1 (0.49) | AGTR1AGTR2SMN1; SMN2ADAM17 | |
| SCHEMBL22786993 | 0.79 | KCNN4 (0.47) | SMN1; SMN2ALDH1A1TSHRHTTPIP4K2C | |
| SCHEMBL13232452 | 0.79 | ALDH1A1 (0.41) | AGTR1SMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL12776866 | 0.79 | SMN1; SMN2 (0.41) | AGTR1AGTR2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7265697 | 0.78 | ALDH1A1 (0.40) | AGTR1SMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL7647188 | 0.78 | POLB (0.41) | AGTR1AGTR2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL20684736 | 0.76 | KCNN4 (0.54) | AGTR1AGTR2SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915425-B2 | Process for the preparation of losartan | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-03-29 | — | — | US | disclosed |
| US-20100222597-A1 | Process for the preparation of losartan | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222597-A1 | Process for the preparation of losartan | AGT, ACE, AGTR1 | AGTR1 3/4885AGTR2 7/4885SMN1; SMN2 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.