SCHEMBL22786993

SCHEMBL22786993

Cc1ccccc1-c1nnnn1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.47
LMNA P02545 1/20 0.46
P2RX7 Q99572 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 1/20 0.44
CASP3 P42574 1/20 0.44
RAB9A P51151 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
ALDH1A1 P00352 3/20 0.43
PKM P14618 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
PIP4K2C Q8TBX8 1/20 0.43
HIF1A Q16665 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
HTR2C P28335 1/20 0.42
BRD4 O60885 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9822895 0.82 P2RX7 (0.40) KCNN4LMNAP2RX7SMN1; SMN2NPC1
SCHEMBL30147353 0.81 HSD11B1 (0.61) KCNN4LMNAP2RX7SMN1; SMN2NPC1
SCHEMBL20684736 0.81 KCNN4 (0.54) KCNN4LMNAP2RX7SMN1; SMN2ALDH1A1
SCHEMBL3070167 0.81 SMN1; SMN2 (0.41) KCNN4LMNAP2RX7SMN1; SMN2ALDH1A1
SCHEMBL12748014 0.79 AGTR1 (0.46) SMN1; SMN2NPC1RAB9AALDH1A1TSHR
SCHEMBL17194907 0.79 P2RX7 (0.42) KCNN4LMNAP2RX7SMN1; SMN2RAB9A
SCHEMBL16127295 0.78 KCNN4 (0.46) KCNN4LMNAP2RX7SMN1; SMN2NPC1
SCHEMBL20375446 0.78 KCNN4 (0.46) KCNN4LMNAP2RX7SMN1; SMN2NPC1
SCHEMBL21091600 0.78 KCNN4 (0.57) KCNN4P2RX7ALDH1A1HTTPIP4K2C
SCHEMBL13491996 0.78 HIF1A (0.41) KCNN4LMNAP2RX7SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912724-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-02-27 US disclosed
US-11858949-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-02 US disclosed
US-11858949-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-02 US disclosed
US-11832511-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
US-11778899-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-03 US disclosed
US-11778899-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-03 US disclosed
EP-3770166-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2021-01-27 EP disclosed
US-20200392173-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-12-17 US disclosed
US-20200395560-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912724-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device L1CAM, FOXM1, CHRM1 KCNN4 658/4885LMNA 1023/4885P2RX7 2239/4885
US-20200395560-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND L1CAM, NOM1, MEN1 KCNN4 3188/4885LMNA 1816/4885P2RX7 4043/4885
US-20200392173-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND L1CAM, MEN1, LEF1 KCNN4 3608/4885LMNA 2055/4885P2RX7 4093/4885
US-11832511-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound L1CAM, NOM1, FOXM1 KCNN4 3297/4885LMNA 2101/4885P2RX7 4119/4885
US-11778899-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound L1CAM, NOM1, MEN1 KCNN4 3188/4885LMNA 1816/4885P2RX7 4043/4885
US-11858949-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound L1CAM, MEN1, LEF1 KCNN4 3608/4885LMNA 2055/4885P2RX7 4093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.