Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 4/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | CTSA | P10619 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12477325 | 0.86 | CES2 (0.47) | PPARGSTK39CES2 | |
| SCHEMBL1274836 | 0.82 | MEN1 (0.45) | RORBRORCCTSAAKR1C3AKR1C2 | |
| SCHEMBL28327522 | 0.81 | PPARG (0.47) | THRATHRBPPARGSTK39CES2 | |
| SCHEMBL28436668 | 0.76 | MEN1 (0.40) | — | |
| SCHEMBL28328822 | 0.75 | CES2 (0.43) | PPARGCES2 | |
| SCHEMBL15671624 | 0.75 | P2RX1 (0.40) | CTSATHRATHRB | |
| SCHEMBL1273899 | 0.73 | SRC (0.42) | PPARGSTK39 | |
| SCHEMBL19892726 | 0.72 | L3MBTL1 (0.40) | MRGPRX4 | |
| SCHEMBL28732508 | 0.72 | MAPK1 (0.35) | PPARGMRGPRX4 | |
| SCHEMBL28341288 | 0.70 | PPARG (0.54) | PPARGCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9314025-B2 | Mixtures of mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20140187776-A1 | MIXTURES OF MESOIONIC PESTICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-8697707-B2 | Mixtures of mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-04-15 | — | — | US | disclosed |
| US-20120115722-A1 | MIXTURES OF MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187776-A1 | MIXTURES OF MESOIONIC PESTICIDES | DDT, C5, CBR3 | RORB 4182/4885RORC 4023/4885CTSA 2198/4885 |
| US-20120115722-A1 | MIXTURES OF MESOIONIC PESTICIDES | DDT, C5, CBR3 | RORB 4182/4885RORC 4023/4885CTSA 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.