SCHEMBL1275145

SCHEMBL1275145

Cc1cc(CSCc2ccccc2)cc(CSCc2ccccc2)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.43
LMNA P02545 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
EGFR P00533 3/20 0.41
ERBB2 P04626 3/20 0.41
CYP2C19 P33261 2/20 0.39
DAO P14920 1/20 0.38
NPC1 O15118 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
KLK7 P49862 1/20 0.37
PKM P14618 2/20 0.36
TTR P02766 1/20 0.36
ALOX5 P09917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6655944 0.88 EGFR (0.46) LMNAKDM4EMAPTEGFRERBB2
SCHEMBL8990194 0.83 BCHE (0.47) LMNAKDM4EMAPTEGFRERBB2
SCHEMBL16572048 0.81 SHBG (0.47) SHBGCYP1A2CYP2C9ALOX5PTGS1
SCHEMBL11809630 0.81 SHBG (0.45) SHBGLMNAKDM4EMAPTDAO
SCHEMBL1275477 0.80 HSPA5 (0.47) LMNAMAPTEGFRERBB2CYP2C19
SCHEMBL5086176 0.78 CYP1A2 (0.50) SHBGCYP1A2CYP2C9PTGS1PTGS2
SCHEMBL11813231 0.78 CA1 (0.48) SHBGLMNAKDM4EMAPTCYP1A2
Methyl Alcohol SCHEMBL29261078 0.78 CYP2C19 (0.56) LMNAKDM4EMAPTCYP2C19NPC1
SCHEMBL28700543 0.77 ALOX5 (0.46) LMNAKDM4EMAPTCYP2C19NPC1
SCHEMBL22667721 0.76 LMNA (0.40) LMNAKDM4EMAPTEGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1249845-B1 Stabilized medium and high voltage cable insulation composition BASF SE (DE) 2012-07-11 EP disclosed
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-7452933-B2 Cross-linked polyethylene having excellent inhibition of sweat-out and insulation properties LG CHEM, LTD. (KR) 2008-11-18 US disclosed
EP-1848768-A4 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
EP-1848768-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG Chem, Ltd. (KR) 2007-10-31 EP disclosed
WO-2007097511-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 WO disclosed
US-20070203278-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 US disclosed
US-7056967-B2 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-06-06 US disclosed
US-20020198344-A1 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP disclosed
EP-0224442-B1 USE OF SUBSTITUTED PHENOLS AS STABILIZERS CIBA-GEIGY AG (CH) 1990-05-16 EP disclosed
US-4857572-A ELASTOMERS AND TACKIFIER RESINS CIBA-GEIGY CORPORATION (US) 1989-08-15 US disclosed
EP-0224442-A1 Use of substituted phenols as stabilizers CIBA-GEIGY AG (CH) 1987-06-03 EP disclosed