Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 5/20 | 0.75 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.75 |
| ▸ | TNKS | O95271 | 3/20 | 0.75 |
| ▸ | PARP1 | P09874 | 3/20 | 0.75 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.72 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.72 |
| ▸ | DHODH | Q02127 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10037938 | 0.88 | CSNK2A2 (0.74) | POLHALOX5TNKSPARP1TNKS2 | |
| SCHEMBL3515838 | 0.87 | HPGD (0.77) | POLHALOX5TNKSPARP1TNKS2 | |
| SCHEMBL31552891 | 0.87 | HPGD (0.77) | POLHALOX5TNKSPARP1TNKS2 | |
| SCHEMBL29664594 | 0.86 | ALOX5 (0.78) | POLHALOX5TNKSPARP1TNKS2 | |
| SCHEMBL491032 | 0.86 | ALOX5 (0.78) | POLHALOX5TNKSPARP1TNKS2 | |
| SCHEMBL29678122 | 0.86 | TNKS (1.00) | POLHALOX5TNKSPARP1TNKS2 | |
| SCHEMBL30591365 | 0.86 | ALOX5 (0.78) | POLHALOX5TNKSPARP1TNKS2 | |
| SCHEMBL34405 | 0.86 | TNKS (1.00) | POLHALOX5TNKSPARP1TNKS2 | |
| SCHEMBL10068612 | 0.84 | CSNK2A2 (0.69) | POLHKDM4EMAPTHSD17B10HPGD | |
| SCHEMBL345706 | 0.84 | TNKS (1.00) | POLHALOX5TNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177237-A1 | ANTIFOULING METHOD AND COMPOSITION USING CHROMEN-4-ONE DERIVATIVES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-07-21 | — | — | US | claimed |
| WO-2005020881-A2 | COMPOSITIONS OF FLAVONOIDS AND FLAVONOID-CONTAINING EXTRACTS AND THE TREATMENT OF DISEASES | SHANGHAI COMMAN PHARMACEUTICAL CO. (US) | 2005-03-10 | — | — | WO | claimed |
| US-20050049206-A1 | Compositions of flavonoids and flavonoid-containing extracts and the treatment of diseases | SHANGHAI COMMAN PHARMACEUTICAL CO. LTD. (CN) | 2005-03-03 | — | — | US | claimed |
| US-8557331-B2 | Antifouling method and composition using chromen-4-one derivatives | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-10-15 | — | — | US | disclosed |
| US-8557331-B2 | Antifouling method and composition using chromen-4-one derivatives | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-10-15 | — | — | US | disclosed |
| US-8466195-B2 | Methods and compositions for treating complications of diabetes and vascular diseases using flavones | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2013-06-18 | — | — | US | disclosed |
| US-8466195-B2 | Methods and compositions for treating complications of diabetes and vascular diseases using flavones | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120016016-A1 | METHODS AND COMPOSITIONS FOR TREATING COMPLICATIONS OF DIABETES AND VASCULAR DISEASES USING FLAVONES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2012-01-19 | — | — | US | disclosed |
| US-20120016016-A1 | METHODS AND COMPOSITIONS FOR TREATING COMPLICATIONS OF DIABETES AND VASCULAR DISEASES USING FLAVONES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2012-01-19 | — | — | US | disclosed |
| US-20110177237-A1 | ANTIFOULING METHOD AND COMPOSITION USING CHROMEN-4-ONE DERIVATIVES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-07-21 | — | — | US | disclosed |
| WO-2010105253-A2 | METHODS AND COMPOSITIONS FOR TREATING COMPLICATIONS OF DIABETES AND VASCULAR DISEASES USING FLAVONES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2010-09-16 | — | — | WO | disclosed |
| WO-2009115051-A1 | ANTIFOULING METHOD AND COMPOSITION USING CHROMEN-4-ONE DERIVATIVES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2009-09-24 | — | — | WO | disclosed |
| US-20050049206-A1 | Compositions of flavonoids and flavonoid-containing extracts and the treatment of diseases | SHANGHAI COMMAN PHARMACEUTICAL CO. LTD. (CN) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016016-A1 | METHODS AND COMPOSITIONS FOR TREATING COMPLICATIONS OF DIABETES AND VASCULAR DISEASES USING FLAVONES | SLC5A2, LIPG, TIE1 | POLH 1988/4885ALOX5 66/4885TNKS 4131/4885 |
| US-20050049206-A1 | Compositions of flavonoids and flavonoid-containing extracts and the treatment of diseases | FNTA, COLGALT1, F3 | POLH 1080/4885ALOX5 407/4885TNKS 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.