Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275004 | 0.90 | TRPA1 (0.36) | TRPA1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL1275774 | 0.90 | MAPT (0.40) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL1275231 | 0.86 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL1275120 | 0.84 | MAPT (0.41) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL9895178 | 0.84 | TRPA1 (0.38) | TRPA1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL1274554 | 0.84 | TRPA1 (0.48) | TRPA1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL9895262 | 0.83 | MAPT (0.37) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL1274319 | 0.82 | MAPT (0.41) | MAPTHDAC1POLB | |
| SCHEMBL1420898 | 0.82 | NR1H4 (0.41) | MAPTALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL297830 | 0.82 | KDM4E (0.43) | TRPA1MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153497-A2 | PESTICIDAL CARBOXAMIDES | Bayer Cropscience AG (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-9227923-B2 | Pesticidal carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| EP-2464624-A2 | PESTICIDAL CARBOXAMIDES | Bayer CropScience AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-20120149910-A1 | Pesticidal Carboxamides | BAYER CROPSCIENCE AG (DE) | 2012-06-14 | — | — | US | disclosed |
| WO-2011018170-A2 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149910-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | TRPA1 222/4885MAPT 4596/4885ALDH1A1 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.