Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299219 | 0.90 | P2RX1 (0.48) | KDM4EALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL289189 | 0.87 | KCNJ11 (0.46) | KDM4EALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL1420898 | 0.86 | NR1H4 (0.41) | KDM4EALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL1275231 | 0.86 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL1274338 | 0.86 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL1275229 | 0.85 | ROCK2 (0.40) | KDM4EALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL1275245 | 0.83 | KCNK3 (0.50) | KDM4EALDH1A1HPGDMAPTALOX15 | |
| SCHEMBL27813370 | 0.83 | P2RX1 (0.51) | HPGDMAPTALOX15HSD17B10CYP1A2 | |
| SCHEMBL1275124 | 0.83 | HDAC1 (0.47) | ALDH1A1MAPTHSD17B10HTTPOLB | |
| SCHEMBL1275206 | 0.83 | MAPT (0.39) | KDM4EALDH1A1HPGDMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427427-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |